Cole Shola A, Stahl Thomas J
Section of Colon and Rectal Surgery, MedStar Washington Hospital Center, Washington, District of Columbia.
Interim Chair, Department of Surgery, MedStar Washington Hospital Center; Regional Director, MedStar Colorectal Surgery Program, Washington, District of Columbia.
Clin Colon Rectal Surg. 2015 Jun;28(2):65-9. doi: 10.1055/s-0035-1547333.
Clostridium difficile infection (CDI) is the most frequent cause of nosocomial diarrhea. It has become a significant dilemma in the treatment of patients, and causes increasing morbidity that, in extreme cases, may result in death. Persistent and recurrent disease hamper attempts at eradication of this infection. Escalating levels of treatment and novel therapeutics are being utilized and developed to treat CDI. Further trials are warranted to definitively determine what protocols can be used to treat persistent and recurrent disease.
艰难梭菌感染（CDI）是医院获得性腹泻最常见的病因。它已成为治疗患者过程中的一个重大难题，并且导致发病率不断上升，在极端情况下可能会导致死亡。持续性和复发性疾病阻碍了根除这种感染的努力。正在使用并研发升级的治疗手段和新型疗法来治疗CDI。有必要进行进一步试验，以明确确定可用于治疗持续性和复发性疾病的方案。
