Thomas Abin, Baby Bilha, Joy Selin C, T P Sreekrishnan, K P Gireesh Kumar
Emergency Medicine, Amrita Institute of Medical Sciences, Ernakulam, IND.
Department of Pharmacy Practice, Amrita School of Pharmacy, Kochi, IND.
Cureus. 2024 Nov 7;16(11):e73223. doi: 10.7759/cureus.73223. eCollection 2024 Nov.
One type of hypokalemic periodic paralysis that is associated with hyperthyroidism is called thyrotoxic periodic paralysis (TPP). TPP can be linked to any cause of hyperthyroidism, although Graves' disease is the most common cause. This sporadic variant of hypokalaemic periodic paralysis, thyrotoxic periodic paralysis, is characterized by rapid onset weakness in the proximal muscles. Due to their similar presentations, it is sometimes mistaken for familial periodic paralysis (FPP); however, biochemical tests and the presence of thyrotoxic characteristics can help distinguish the two conditions. Treatment options for this reversible illness include rapid potassium replacement and thyroid hormone normalization. To mitigate this potentially fatal complication, knowledge regarding the identification, prompt treatment, and avoidance of future episodes of TPP is crucial.
一种与甲状腺功能亢进相关的低钾性周期性麻痹称为甲状腺毒症性周期性麻痹（TPP）。TPP可与任何甲状腺功能亢进病因相关，尽管格雷夫斯病是最常见的病因。这种低钾性周期性麻痹的散发性变体，即甲状腺毒症性周期性麻痹，其特征是近端肌肉迅速出现无力。由于它们的表现相似，有时会被误诊为家族性周期性麻痹（FPP）；然而，生化检查和甲状腺毒症特征的存在有助于区分这两种情况。这种可逆性疾病的治疗选择包括快速补钾和甲状腺激素正常化。为了减轻这种潜在的致命并发症，了解TPP的识别、及时治疗以及避免未来发作的知识至关重要。
