Meseeha Marcelle, Parsamehr Behnaz, Kissell Kerri, Attia Maximos
Department of Internal Medicine, Guthrie Medical Group, PC, Sayre, PA, USA.
Department of Endocrinology, Diabetes, and Metabolism, Guthrie Medical Group, PC, Sayre, PA, USA.
J Community Hosp Intern Med Perspect. 2017 Jun 6;7(2):103-106. doi: 10.1080/20009666.2017.1316906. eCollection 2017 Mar.
Acute hypokalemic paralysis is a rare cause of acute weakness. Morbidity and mortality associated with unrecognized disease can occur and include respiratory failure and possibly death. Common causes of hypokalemic paralysis include thyrotoxic periodic paralysis (TPP) which is a disorder most frequently seen in Asian males. TPP is characterized by sudden onset of hypokalemia and paralysis that primarily affects the lower extremities. Treatment of TPP includes replacing potassium rapidly, using nonselective beta-blockade and correcting the underlying hyperthyroidism as soon as possible. TPP is curable once euthyroid state is achieved. It is vital for physicians to be able to differentiate TPP from familial hypokalemic periodic paralysis, a more common cause of periodic paralysis in Caucasians and western countries. We describe a 19-year-old Caucasian man who presented with acute onset lower extremity paralysis secondary to acute hypokalemia and was found to have new onset Graves' disease. TPP: Thyrotoxic periodic paralysis.
急性低钾性麻痹是急性肌无力的罕见病因。未被识别的疾病相关的发病率和死亡率可能会出现，包括呼吸衰竭甚至可能死亡。低钾性麻痹的常见病因包括甲状腺毒症性周期性麻痹（TPP），这是一种在亚洲男性中最常见的疾病。TPP的特征是低钾血症和麻痹突然发作，主要影响下肢。TPP的治疗包括迅速补钾、使用非选择性β受体阻滞剂以及尽快纠正潜在的甲状腺功能亢进。一旦达到甲状腺功能正常状态，TPP是可治愈的。对于医生来说，能够区分TPP和家族性低钾性周期性麻痹至关重要，后者是白种人和西方国家周期性麻痹更常见的病因。我们描述了一名19岁的白种男性，他因急性低钾血症出现急性下肢麻痹，被发现患有新发格雷夫斯病。TPP：甲状腺毒症性周期性麻痹
