Arunachalam Ganesh Ramki, Selvaraj Karthikeyan, Chandran Srinivasan, Yesuvadiyan Jesu Pencilin
General Surgery, Sree Balaji Medical College and Hospital, Chennai, IND.
Cureus. 2024 Nov 6;16(11):e73169. doi: 10.7759/cureus.73169. eCollection 2024 Nov.
Extraneural perineuriomas are rare, benign soft tissue tumors arising from perineurial cells, which form the protective lining of peripheral nerves. These tumors are infrequently encountered in the foot, posing diagnostic challenges due to their rarity and non-specific clinical presentation. Here, we describe the case of a 45-year-old woman, who had a swelling over the right foot dorsum for four years for which an excision biopsy was done. Her histopathological variant and immunohistochemistry were consistent with extraneural perineurioma. This article aims to present a comprehensive review of extraneural perineuriomas, focusing on a case study involving the foot, and to discuss the clinical and histopathological characteristics, differential diagnosis, treatment options, and prognosis of this uncommon entity.
神经外膜性神经束膜瘤是一种罕见的良性软组织肿瘤，由神经束膜细胞产生，神经束膜细胞形成周围神经的保护性被膜。这些肿瘤在足部很少见，由于其罕见性和非特异性临床表现，给诊断带来了挑战。在此，我们描述了一名45岁女性的病例，她右脚背肿胀四年，为此进行了切除活检。她的组织病理学变异和免疫组化结果与神经外膜性神经束膜瘤一致。本文旨在全面综述神经外膜性神经束膜瘤，重点是一个涉及足部的病例研究，并讨论这种罕见实体的临床和组织病理学特征、鉴别诊断、治疗选择及预后。
