Collier P E, Turowski P, Diamond D L
Cancer. 1985 Feb 1;55(3):516-21. doi: 10.1002/1097-0142(19850201)55:3<516::aid-cncr2820550308>3.0.co;2-k.
Three new cases of small intestinal adenocarcinoma complicating Crohn's disease are reported. Seventy-five other cases have been reported to date. Analysis of these cases in comparison with de novo adenocarcinoma of the small bowel shows that they: (1) occur at a younger age; (2) occur in distal small bowel; (3) show a male predilection; and (4) have a worse prognosis. The increasing number of these cases suggests that small intestinal regional enteritis predisposes to adenocarcinoma. Improved prognosis can only be achieved with earlier diagnosis.
报告了3例并发克罗恩病的小肠腺癌新病例。迄今为止已报告了另外75例。将这些病例与原发性小肠腺癌进行比较分析表明，它们：(1)发病年龄较轻；(2)发生在小肠远端；(3)男性居多；(4)预后较差。这些病例数量的增加表明小肠局限性肠炎易引发腺癌。只有早期诊断才能改善预后。
