2019冠状病毒病疫情对亚太地区造血细胞移植领域的影响：亚太骨髓移植协作组2020/2021年活动调查
Impact of the COVID-19 outbreak on the field of hematopoietic cell transplantation in the Asia-Pacific region: APBMT Activity Survey 2020/2021.
作者信息
Iida Minako, Ho Aloysius, Huang Xiao Jun, Liu Kaiyan, Lv Meng, Huang He, Kuwatsuka Yachiyo, Moon Joon Ho, Choi Yoon Seok, Lee Jong Wook, Khattry Navin, M Lakshmi Kavitha, Wilcox Leonie, Hamidieh Amir Ali, Behfar Maryam, Ko Bor-Sheng, Ho Kim Wah, Gan Gin Gin, Bunworasate Udomsak, Hongeng Suradej, Anurathapan Usanarat, Farzana Tasneem, Sim Joycelyn, Lee Vincent, Leung Man Kit Garret, Dung Phu Chi, Huynh Van Man, Rathnayake Wasantha, Abeysinghe Prasad, Bravo Marjorie Rose, Dumagay Teresita, Gyi Aye Aye, Santosa Damai, Ardini Desta, Poudyal Bishesh Sharma, Akter Mafruha, Batshkh Khishigjargal, Drokov Mikhail, Li Chi-Cheng, Okamoto Shinichiro, Srivastava Alok, Dodds Anthony, Atsuta Yoshiko
机构信息
Department of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Japan.
Department of Hematology, Singapore General Hospital, Singapore, Singapore.
出版信息
Blood Cell Ther. 2024 Nov 25;7(4):129-137. doi: 10.31547/bct-2024-020.
COVID-19 became a global pandemic in 2020 and significantly affected the activity of hematopoietic cell transplants (HCT) worldwide. Despite these challenges, a total of 28,793 transplants, including 18,518 allogeneic and 10,275 autologous transplants, were performed in 719 facilities in 2020 in the Asia-Pacific (AP) region. This represented a 5.1% increase in allogeneic transplants and a 3.1% increase in autologous transplants, an overall increase of 4.4% compared to the numbers in 2019. With respect to the donor source, haploidentical transplants increased significantly by 18.6%, related transplants by 8.8%, and cord blood transplants (CBT) by 9.2%. However, the number of unrelated transplants, excluding CBT, decreased for the first time by 8.2%. As a result, COVID-19 facilitated the growth of haploidentical transplants due to cross-border restrictions. Regarding the changes in the total number of transplants by country/region in 2020, it increased by 2,048 transplants in China, followed by Japan (210 transplants) and Korea (230 transplants); however, 14 of the 22 countries and regions decreased their number of transplants in 2020 compared to the previous year. There was no correlation between the increase or decrease in the number of transplants in 2020 and the Gross National Income (GNI) per capita of each country/region in 2020, as well as Domestic General Government Health Expenditure as a percentage of General Government Expenditure (GGHE-D/GGE). In 2021, the total number of transplants in this region was 34,754. With the exception of a few countries/regions that decreased the number of transplants in 2020, most countries/regions have started to see a recovery in 2021. The COVID-19 pandemic significantly affected the supply chain and logistics involved in HCT rather than its numbers; however, we have found ways to overcome logistical challenges to carry out transplant medicine without delay, even under these circumstances.
2020年，新冠疫情成为全球大流行疾病，对全球造血细胞移植（HCT）活动产生了重大影响。尽管面临这些挑战，2020年亚太地区719家机构共进行了28793例移植手术，其中包括18518例异基因移植和10275例自体移植。与2019年相比，异基因移植增加了5.1%，自体移植增加了3.1%，总体增长了4.4%。在供体来源方面，单倍体相合移植显著增加了18.6%，亲属移植增加了8.8%，脐带血移植（CBT）增加了9.2%。然而，不包括CBT的非亲属移植数量首次下降了8.2%。因此，由于跨境限制，新冠疫情推动了单倍体相合移植的增长。关于2020年各国/地区移植总数的变化，中国增加了2048例移植手术，其次是日本（增加210例）和韩国（增加230例）；然而，22个国家和地区中有14个在2020年的移植数量较上一年有所下降。2020年移植数量的增减与各国/地区2020年的人均国民收入（GNI）以及国内一般政府卫生支出占一般政府支出的百分比（GGHE-D/GGE）之间没有相关性。2月21年，该地区的移植总数为34754例。除了少数在2020年减少移植数量的国家/地区外，大多数国家/地区在2021年已开始出现复苏。新冠疫情对造血细胞移植所涉及的供应链和物流产生了重大影响，而非移植数量；然而，即使在这种情况下，我们也找到了克服后勤挑战的方法，以便毫不拖延地开展移植医学。
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