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COVID-19 大流行期间造血细胞移植的现实问题和潜在解决方案:来自全球血液和骨髓移植网络及国际血液和骨髓移植研究中心卫生服务和国际研究委员会的观点。

Real-World Issues and Potential Solutions in Hematopoietic Cell Transplantation during the COVID-19 Pandemic: Perspectives from the Worldwide Network for Blood and Marrow Transplantation and Center for International Blood and Marrow Transplant Research Health Services and International Studies Committee.

机构信息

Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.

Department of Adult Hematology and Stem Cell Transplant, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.

出版信息

Biol Blood Marrow Transplant. 2020 Dec;26(12):2181-2189. doi: 10.1016/j.bbmt.2020.07.021. Epub 2020 Jul 24.

DOI:10.1016/j.bbmt.2020.07.021
PMID:32717432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7380217/
Abstract

The current COVID-19 pandemic, caused by SARS-CoV-2, has impacted many facets of hematopoietic cell transplantation (HCT) in both developed and developing countries. Realizing the challenges as a result of this pandemic affecting the daily practice of the HCT centers and the recognition of the variability in practice worldwide, the Worldwide Network for Blood and Marrow Transplantation (WBMT) and the Center for International Blood and Marrow Transplant Research's (CIBMTR) Health Services and International Studies Committee have jointly produced an expert opinion statement as a general guide to deal with certain aspects of HCT, including diagnostics for SARS-CoV-2 in HCT recipient, pre- and post-HCT management, donor issues, medical tourism, and facilities management. During these crucial times, which may last for months or years, the HCT community must reorganize to proceed with transplantation activity in those patients who urgently require it, albeit with extreme caution. This shared knowledge may be of value to the HCT community in the absence of high-quality evidence-based medicine. © 2020 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.

摘要

当前由 SARS-CoV-2 引起的 COVID-19 大流行已经对发达国家和发展中国家的造血细胞移植(HCT)的许多方面产生了影响。认识到这一流行病对 HCT 中心日常实践的影响所带来的挑战,以及认识到全球实践的多样性,全球血液和骨髓移植网络(WBMT)和国际血液与骨髓移植研究中心的(CIBMTR)卫生服务和国际研究委员会共同制定了专家意见声明,作为处理 HCT 某些方面的一般指南,包括 HCT 受者中 SARS-CoV-2 的诊断、移植前和移植后管理、供者问题、医疗旅游和设施管理。在这些可能持续数月或数年的关键时期,HCT 社区必须进行重组,为那些急需移植的患者开展移植活动,尽管要极其谨慎。在缺乏高质量循证医学的情况下,这一共享知识可能对 HCT 社区具有价值。©2020 美国移植与细胞治疗学会。由 Elsevier Inc. 出版。

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