Teyssier J R, Adnet J J, Pigeon F, Bajolle F
Cancer Genet Cytogenet. 1985 Jan 1;14(1-2):147-52. doi: 10.1016/0165-4608(85)90225-0.
The chromosomal changes in an ovarian granulosa cell tumor were studied after short-term culture in defined medium. The abnormalities found included X monosomy, structural rearrangements of chromosome #1, and an interstitial deletion of the long arm of chromosome #6. This pattern is closely related to that found in ovarian carcinoma and argues for the malignant nature of such tumors at the cellular level.
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