胚胎性横纹肌肉瘤的细胞遗传学研究

A cytogenetic study of embryonal rhabdomyosarcoma.

作者信息

Potluri V R, Gilbert F

出版信息

Cancer Genet Cytogenet. 1985 Jan 1;14(1-2):169-73. doi: 10.1016/0165-4608(85)90228-6.

Abstract

In the cytogenetic analysis of an embryonal rhabdomyosarcoma after short-term culture, individual cells were found to contain multiple copies of chromosomes #2, #6, #8, #12, #13, #18, #20 and #21, and del(1)(:p21----qter). The tumor was hypotriploid (mode, 56 chromosomes). The relationship between these findings and published reports of karyotypes from rhabdomyosarcoma is discussed.

摘要

在对短期培养后的胚胎性横纹肌肉瘤进行细胞遗传学分析时，发现单个细胞含有2号、6号、8号、12号、13号、18号、20号和21号染色体的多个拷贝，以及del(1)(:p21----qter)。该肿瘤为亚三倍体（众数为56条染色体）。本文讨论了这些发现与已发表的横纹肌肉瘤核型报告之间的关系。