Gil-Benso R, Carda-Batalla C, Navarro-Fos S, Pellín-Perez A, Llombart-Bosch A
Department of Pathology, Medical School, University of Valencia, Spain.
Cancer Genet Cytogenet. 1999 Mar;109(2):150-3. doi: 10.1016/s0165-4608(98)00163-0.
The cytogenetic analysis of a spindle-cell rhabdomyosarcoma of the parotid gland in a 6-year-old boy is reported. The tumor cells showed an abnormal karyotype with a hypotriploid modal chromosome number and clonal structural rearrangements affecting chromosomes 1, 8, 12, 21, and 22. The tumor karyotype was: 59, XY, -1, -3, -4, -5, -6, +8, +8, +del(8)(q22q24), -9, -10, del(12)(q13), -15, -16, -17, -18, der(21)t(12;21)(p11;p11), -22, der(22)t(1;22)(q12;p11).
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