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[特应性皮炎与糖尿病——存在关联吗?]

[Atopic dermatitis and diabetes mellitus-is there a link?].

作者信息

Sendrea Adelina-Maria, Salavastru Carmen Maria

机构信息

Carol Davila Universität für Medizin und Pharmacie, 8 Eroilor Sanitari Boulevard, 050474, Bukarest, Rumänien.

Abteilung Pädiatrische Dermatologie, Colentina Klinik, Bukarest, Rumänien.

出版信息

Dermatologie (Heidelb). 2025 Jan;76(1):21-26. doi: 10.1007/s00105-024-05440-6. Epub 2024 Dec 9.

Abstract

BACKGROUND

Atopic dermatitis and diabetes mellitus are chronic, immune-mediated, inflammatory diseases that significantly affect patients' quality of life and also represent a considerable socioeconomic burden. Despite intensive research in recent decades, the possible link between these two medical conditions remains a controversial topic due to sparse and sometimes contradictory data. Nevertheless, the potential link between them is based on some recognized common pathophysiological features.

AIM

To summarize and evaluate a possible association between atopic dermatitis and diabetes mellitus.

MATERIALS AND METHODS

A literature review on the potential association between atopic dermatitis and diabetes mellitus was conducted.

RESULTS

Several studies have reported a correlation between atopic dermatitis and type 1 or type 2 diabetes mellitus. However, other studies have shown no association between these two conditions or even suggested that atopic dermatitis could reduce the risk of developing diabetes mellitus in certain patients. In addition, these two chronic diseases also have certain clinical features that suggest a possible correlation. However, there is currently no clear scientific evidence of a significant positive association between atopic dermatitis and diabetes mellitus, mainly due to the lack of large and diverse demographic studies.

CONCLUSION

Clinicians should be aware of this potential correlation in both adult and pediatric patients and consider the importance of an interdisciplinary approach for the management of atopic dermatitis. Further research is needed to determine possible associations between atopic dermatitis and diabetes mellitus in specific populations.

摘要

背景

特应性皮炎和糖尿病是慢性、免疫介导的炎症性疾病,严重影响患者的生活质量,也带来了相当大的社会经济负担。尽管近几十年来进行了深入研究,但由于数据稀少且有时相互矛盾,这两种疾病之间可能存在的联系仍是一个有争议的话题。然而,它们之间的潜在联系基于一些公认的共同病理生理特征。

目的

总结并评估特应性皮炎与糖尿病之间可能存在的关联。

材料与方法

对特应性皮炎与糖尿病之间的潜在关联进行了文献综述。

结果

多项研究报告了特应性皮炎与1型或2型糖尿病之间的相关性。然而,其他研究表明这两种疾病之间没有关联,甚至表明特应性皮炎可能会降低某些患者患糖尿病的风险。此外,这两种慢性病也有某些临床特征提示可能存在相关性。然而,目前尚无明确的科学证据表明特应性皮炎与糖尿病之间存在显著的正相关,主要原因是缺乏大规模、多样化的人群研究。

结论

临床医生应在成人和儿童患者中意识到这种潜在的相关性,并认识到采用跨学科方法管理特应性皮炎的重要性。需要进一步研究以确定特定人群中特应性皮炎与糖尿病之间可能存在的关联。

相似文献

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[Atopic dermatitis and diabetes mellitus-is there a link?].[特应性皮炎与糖尿病——存在关联吗?]
Dermatologie (Heidelb). 2025 Jan;76(1):21-26. doi: 10.1007/s00105-024-05440-6. Epub 2024 Dec 9.

本文引用的文献

8
Pathophysiology of diabetes: An overview.糖尿病的病理生理学:概述
Avicenna J Med. 2020 Oct 13;10(4):174-188. doi: 10.4103/ajm.ajm_53_20. eCollection 2020 Oct-Dec.
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Atopic eczema and obesity: a population-based study.特应性皮炎与肥胖:一项基于人群的研究。
Br J Dermatol. 2021 May;184(5):871-879. doi: 10.1111/bjd.19597. Epub 2020 Dec 1.

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