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严重低磷血症的治疗。

Treatment of severe hypophosphatemia.

作者信息

Kingston M, Al-Siba'i M B

出版信息

Crit Care Med. 1985 Jan;13(1):16-8. doi: 10.1097/00003246-198501000-00005.

DOI:10.1097/00003246-198501000-00005
PMID:3965243
Abstract

A 4-h infusion of 310 to 465 mg (10 to 15 mMol) phosphorus given to 28 of 31 consecutive seriously ill hypophosphatemic patients increased the serum phosphorus level above 1.2 mg/dl in all but one patient. There was no significant change in the mean serum calcium, potassium or blood pressure, no patient deteriorated, and six patients were stronger and more alert after the infusion. In seriously ill patients we recommend a 4-h infusion of 15 mg/kg (0.5 mMol/kg) phosphorus if the serum phosphorus is less than 0.5 mg/dl, or a 7.7-mg/kg (0.25 mMol/kg) infusion if the serum phosphorus is between 0.5 and 1.0 mg/dl.

摘要

对31例连续的重症低磷血症患者中的28例给予4小时输注310至465毫克(10至15毫摩尔)磷,除1例患者外,所有患者的血清磷水平均升至1.2毫克/分升以上。平均血清钙、钾或血压无显著变化,无患者病情恶化,6例患者在输注后更强壮、更警觉。对于重症患者,如果血清磷低于0.5毫克/分升,我们建议4小时输注15毫克/千克(0.5毫摩尔/千克)磷;如果血清磷在0.5至1.0毫克/分升之间,则建议输注7.7毫克/千克(0.25毫摩尔/千克)。

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