Zheng Lingling, Li Siqi, Xu Yanfeng, Wang Wei, Yang Jigang
From the Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Clin Nucl Med. 2025 Apr 1;50(4):346-348. doi: 10.1097/RLU.0000000000005630. Epub 2024 Dec 9.
A 5-year-old girl with high-risk neuroblastoma after therapy was evaluated by 123 I-MIBG SPECT/CT and 68 Ga-DOTATATE PET/CT. Contrast-enhancement brain MRI demonstrated 2 metastatic lesions in the right parietal lobe of brain. One lesion showed abnormal MIBG accumulation associated with high density in the right central posterior gyrus, whereas the other lesion did not show MIBG uptake. In contrast, increased 68 Ga-DOTATATE uptake was seen in both lesions. Neuroblastoma cells were found by cytological examination of the cerebrospinal fluid.
一名接受治疗后的5岁高危神经母细胞瘤女孩接受了123I-MIBG SPECT/CT和68Ga-DOTATATE PET/CT检查。增强脑MRI显示右侧顶叶有2个转移灶。一个病灶在右侧中央后回显示出与高密度相关的异常MIBG聚集，而另一个病灶未显示MIBG摄取。相比之下，两个病灶均可见68Ga-DOTATATE摄取增加。通过脑脊液细胞学检查发现了神经母细胞瘤细胞。
