Achermann J, Sugiyama T
Dev Biol. 1985 Jan;107(1):13-27. doi: 10.1016/0012-1606(85)90371-9.
Morphogenetic potentials of hydra tissue involved in head or foot formation were examined in a standard wild-type strain (105) and a mutant strain (reg-16) which has a very low head regenerative but a nearly normal foot regenerative capacity (T. Sugiyama and T. Fujisawa, 1977, J. Embryol. Exp. Morphol. 42, 65-77). Hydra tissue has two types of morphogenetic potentials to control head formation: the potential to form head structure (head-activation potential) and the potential to inhibit head formation (head-inhibition potential). It also has two types of morphogenetic potentials to control foot formation: foot-activation and foot-inhibition potentials. A lateral tissue grafting procedure (G. Webster and L. Wolpert, 1966, J. Embryol. Exp. Morphol. 16, 91-104), was used to examine and compare the relative levels of these potentials in the normal and the mutant strains. The potential levels were examined along the body axis of the intact animals and also in the regenerating animals after head removal. The results obtained show that the potentials involved in head formation are highly abnormal, whereas the potentials involved in foot formation are apparently normal in the mutant strain (reg-16). This suggests that the abnormal potentials are related in some way to, and may be responsible for, the reduced head regenerative capacity in the mutant strain reg-16.
在一个标准野生型品系（105）和一个突变品系（reg - 16）中研究了参与头部或足部形成的水螅组织的形态发生潜能。突变品系（reg - 16）的头部再生能力非常低，但足部再生能力几乎正常（T. 杉山和T. 藤泽，1977年，《胚胎学与实验形态学杂志》42卷，65 - 77页）。水螅组织有两种控制头部形成的形态发生潜能：形成头部结构的潜能（头部激活潜能）和抑制头部形成的潜能（头部抑制潜能）。它也有两种控制足部形成的形态发生潜能：足部激活和足部抑制潜能。采用侧向组织移植方法（G. 韦伯斯特和L. 沃尔珀特，1966年，《胚胎学与实验形态学杂志》16卷，91 - 104页）来检测和比较正常品系和突变品系中这些潜能的相对水平。沿着完整动物的体轴以及头部切除后的再生动物来检测潜能水平。获得的结果表明，在突变品系（reg - 16）中，参与头部形成的潜能高度异常，而参与足部形成的潜能明显正常。这表明异常潜能在某种程度上与突变品系reg - 16中头部再生能力降低有关，并且可能是其原因。
