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中国9个长寿地区65岁以上老年人饮食模式与血脂水平的关联

[Association of dietary patterns with blood lipid level among the older adults over 65 years old in 9 longevity areas of China].

作者信息

Xu Z N, Li Y, Wang J, Xu L J, Chen C, Zhang Z H, Li Y Q, Xia Y, Lu Z H, Liu S X, Guo X J, Li Z H, Shi X M, Mao C, Lyu Y B

机构信息

Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou510515, China National Institute of Environmental Health, Chinese Center for Disease Control and Prevention/China CDC Key Laboratory of Environment and Population Health, Beijing100021, China.

National Institute of Environmental Health, Chinese Center for Disease Control and Prevention/China CDC Key Laboratory of Environment and Population Health, Beijing100021, China Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing211166, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2024 Dec 10;104(46):4212-4220. doi: 10.3760/cma.j.cn112137-20240629-01459.

DOI:10.3760/cma.j.cn112137-20240629-01459
PMID:39653526
Abstract

To explore the impact of adherence to plant-based and animal-based dietary patterns on blood lipid level in Chinese older adults aged≥65. The study subjects were from the Chinese Longitudinal Health Biomarker Survey on Aging conducted between 2008 and 2018. The project carried out a baseline survey on elderly people in nine longevity areas of China from 2008 to 2009, and conducted 3 follow-up visits respectively in 2011-2012, 2014, and 2017-2018. The information about their demographic characteristics, lifestyles, physical examinations and fasting venous blood samples were collected. Food Frequency Questionnaire was used to collect data on food intake frequency. Priori plant-based and priori animal-based dietary patterns were constructed, and plant-based diet index (PDI) and animal-based diet index (ADI) were calculated in 2 011 older adults. Linear mixed-effects models were used to analyze the associations of different dietary pattern indices with blood lipid level in older adults. The average age of 2 011 subjects was (83.1±11.5) years, 52.8% (1 061) of them were women. The PDI and ADI [ (, )] were 41.0 (38.0, 45.0) and 43.0 (39.0, 46.0), respectively. After adjusting for covariates, the results of the linear mixed effects model analysis showed that for each increment of 10-unit in PDI, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels decreased by 0.097 (95%:-0.151--0.042) mmol/L and 0.078 (95%:-0.118--0.038) mmol/L, respectively. For each increment of 10-unit in ADI, TC and LDL-C levels increased by 0.096 (95%: 0.042-0.151) mmol/L and 0.078 (95%: 0.038-0.118) mmol/L, respectively. In Chinese older adults≥65 years, higher adherence to the plant-based dietary pattern may lead to reductions in TC and LDL-C levels, while higher adherence to the animal-based dietary pattern may lead to increases in TC and LDL-C levels.

摘要

探讨坚持植物性和动物性饮食模式对65岁及以上中国老年人血脂水平的影响。研究对象来自2008年至2018年开展的中国老年健康生物标志物纵向调查。该项目于2008年至2009年对中国九个长寿地区的老年人进行了基线调查,并分别在2011 - 2012年、2014年以及2017 - 2018年进行了3次随访。收集了他们的人口统计学特征、生活方式、体格检查及空腹静脉血样本等信息。采用食物频率问卷收集食物摄入频率数据。构建了先验植物性饮食模式和先验动物性饮食模式,并计算了2011名老年人的植物性饮食指数(PDI)和动物性饮食指数(ADI)。使用线性混合效应模型分析不同饮食模式指数与老年人血脂水平的关联。2011名受试者的平均年龄为(83.1±11.5)岁,其中5

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