Han Yuanhang, Zhu Bin, Huang Delong, Lan Youyu, Zhong Haoshu, Zhang Yongqin, Zhou Hemu, Liu Chengzhen, Zhou Ping
Department of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China.
Department of Bone and Joint Surgery, Mengla County People's Hospital of Yunnan Province, Xishuangbanna, 666300, Yunnan, China.
Neurol Sci. 2025 Mar;46(3):1087-1101. doi: 10.1007/s10072-024-07905-x. Epub 2024 Dec 9.
Reminiscence therapy(RT) is used in the care of people with dementia to help improve their quality of life, but the efficacy of RT in various cognitive decline populations is unclear, and long-term effects are not sufficiently evidenced.This systematic review and meta-analysis aims to determine the efficacy of RT in improving cognitive decline and provide evidence for its implementation in care.
A comprehensive search strategy utilizing MeSH terms and free-text keywords was employed to systematically search the Embase, PubMed, and Cochrane databases up to January 24, 2024. Randomized controlled trials(RCTs) investigating RT monotherapy for improving cognitive decline were included. The primary outcomes of interest were the standard Mini-Mental State Examination (MMSE) scores. Additionally, all data analyses will be performed using RevMan5.4 software.
We identified 612 studies, and 24 studies met the inclusion criteria, involving 2650 participants. This meta-analysis shows that RT significantly improves immediate and long-term cognitive decline with Standardized Mean Difference(SMD) and 95% CI of 0.55 [0.37, 0.73] and 0.50 [0.11, 0.88], respectively. However, there is no significant difference in efficacy between subgroups (P > 0.05).
Our findings suggestS that RT significantly improves cognitive decline, with no significant differences between subgroups. This suggests that RT is universal in improving cognition and that the way RT is implemented has no significant effect on outcomes. These findings supportS the use of RT as a reliable non-pharmacological treatment option to enhance cognitive function.
回忆疗法（RT）用于痴呆症患者的护理，以帮助改善他们的生活质量，但RT在各种认知衰退人群中的疗效尚不清楚，且长期效果缺乏充分证据。本系统评价和荟萃分析旨在确定RT在改善认知衰退方面的疗效，并为其在护理中的应用提供证据。
采用综合检索策略，利用医学主题词（MeSH）和自由文本关键词，系统检索截至2024年1月24日的Embase、PubMed和Cochrane数据库。纳入研究RT单一疗法改善认知衰退的随机对照试验（RCT）。主要关注的结局是标准简易精神状态检查表（MMSE）评分。此外，所有数据分析将使用RevMan5.4软件进行。
我们确定了612项研究，24项研究符合纳入标准，涉及2650名参与者。该荟萃分析表明，RT能显著改善即时和长期认知衰退，标准化均数差（SMD）及95%置信区间分别为0.55 [0.37, 0.73]和0.50 [0.11, 0.88]。然而，亚组间疗效无显著差异（P > 0.05）。
我们的研究结果表明，RT能显著改善认知衰退，亚组间无显著差异。这表明RT在改善认知方面具有普遍性，且RT的实施方式对结局无显著影响。这些研究结果支持将RT作为一种可靠的非药物治疗选择来增强认知功能。
