双向细胞器运输可发生在含有单根微管的细胞突起中。
Bidirectional organelle transport can occur in cell processes that contain single microtubules.
作者信息
Koonce M P, Schliwa M
出版信息
J Cell Biol. 1985 Jan;100(1):322-6. doi: 10.1083/jcb.100.1.322.
Abstract
Intracellular organelle transport was studied in a new model system, the giant freshwater ameba Reticulomyxa. The ameba extends a large reticulate network of cytoplasmic strands in which various phase-dense organelles can be seen to move at a rate of up to 25 microns/s. This combined light and high voltage electron microscopic study shows that organelles move bidirectionally in even the finest network strands that contain only a single microtubule. In terms of microtubule-associated intracellular transport, this observation defines a minimum set of conditions necessary for such movement. The implications of this finding for possible models of force generation are discussed.
摘要
在一种新的模型系统——大型淡水变形虫网柄菌中研究了细胞内细胞器运输。这种变形虫伸出一个由细胞质丝组成的大型网状网络，在其中可以看到各种致密相细胞器以高达25微米/秒的速度移动。这项结合了光学显微镜和高压电子显微镜的研究表明，即使在仅包含单个微管的最细网络丝中，细胞器也能双向移动。就微管相关的细胞内运输而言，这一观察结果定义了这种移动所需的一组最低条件。讨论了这一发现对可能的力产生模型的影响。
相似文献
1
Bidirectional organelle transport can occur in cell processes that contain single microtubules.双向细胞器运输可发生在含有单根微管的细胞突起中。
J Cell Biol. 1985 Jan;100(1):322-6. doi: 10.1083/jcb.100.1.322.
2
Reactivation of organelle movements along the cytoskeletal framework of a giant freshwater ameba.沿着大型淡水变形虫细胞骨架框架的细胞器运动的重新激活。
J Cell Biol. 1986 Aug;103(2):605-12. doi: 10.1083/jcb.103.2.605.
3
Cytoskeletal architecture and motility in a giant freshwater amoeba, Reticulomyxa.大型淡水变形虫网柄菌的细胞骨架结构与运动性
Cell Motil Cytoskeleton. 1986;6(5):521-33. doi: 10.1002/cm.970060511.
4
An ATPase with properties expected for the organelle motor of the giant amoeba, Reticulomyxa.一种具有巨型变形虫网柄菌细胞器运动蛋白预期特性的ATP酶。
Nature. 1988 Mar 10;332(6160):176-8. doi: 10.1038/332176a0.
5
Organelles are transported on sliding microtubules in Reticulomyxa.在网柱黏菌中，细胞器在滑动的微管上运输。
Cell Motil Cytoskeleton. 2000 Dec;47(4):296-306. doi: 10.1002/1097-0169(200012)47:4<296::AID-CM4>3.0.CO;2-4.
6
Force generation of organelle transport measured in vivo by an infrared laser trap.通过红外激光阱在体内测量细胞器运输的力产生。
Nature. 1990 Nov 22;348(6299):346-8. doi: 10.1038/348346a0.
7
Nucleotide specificities of anterograde and retrograde organelle transport in Reticulomyxa are indistinguishable.网柄菌中顺行和逆行细胞器运输的核苷酸特异性没有区别。
J Cell Biol. 1991 Mar;112(6):1199-203. doi: 10.1083/jcb.112.6.1199.
8
Active sliding between cytoplasmic microtubules.细胞质微管之间的主动滑动。
Nature. 1987;328(6132):737-9. doi: 10.1038/328737a0.
9
Reticulomyxa: a new model system of intracellular transport.网柄菌：细胞内运输的新模型系统
J Cell Sci Suppl. 1986;5:145-59. doi: 10.1242/jcs.1986.supplement_5.9.
10
Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.来自鱿鱼轴质的单个天然微管的滑动运动及双向运输：微管在细胞质运输中起积极作用的证据。
J Cell Biol. 1985 May;100(5):1736-52. doi: 10.1083/jcb.100.5.1736.
引用本文的文献
1
Movement of mitochondria in the ovarian trophic cord of Dysdercus intermedius (Heteroptera) resembles nerve axonal transport.红蝽（半翅目）卵巢营养索中线粒体的移动类似于神经轴突运输。
Rouxs Arch Dev Biol. 1987 Oct;196(7):407-413. doi: 10.1007/BF00399140.
2
Organelle-cytoskeletal interactions: actin mutations inhibit meiosis-dependent mitochondrial rearrangement in the budding yeast Saccharomyces cerevisiae.细胞器与细胞骨架的相互作用：肌动蛋白突变抑制出芽酵母酿酒酵母中减数分裂依赖的线粒体重排。
Mol Biol Cell. 1995 Oct;6(10):1381-96. doi: 10.1091/mbc.6.10.1381.
3
The arrangement of F-actin and microtubules during germination of Mucor rouxii sporangiospores.鲁氏毛霉孢子囊孢子萌发过程中F-肌动蛋白和微管的排列
Arch Microbiol. 1994;161(5):363-9. doi: 10.1007/BF00288945.
4
Reactivation of organelle movements along the cytoskeletal framework of a giant freshwater ameba.沿着大型淡水变形虫细胞骨架框架的细胞器运动的重新激活。
J Cell Biol. 1986 Aug;103(2):605-12. doi: 10.1083/jcb.103.2.605.
5
Dynamic shape changes of cytoplasmic organelles translocating along microtubules.沿微管转运的细胞质细胞器的动态形状变化。
J Cell Biol. 1987 Sep;105(3):1267-71. doi: 10.1083/jcb.105.3.1267.
6
The structure of cytoplasm in directly frozen cultured cells. II. Cytoplasmic domains associated with organelle movements.直接冷冻培养细胞中细胞质的结构。II. 与细胞器运动相关的细胞质区域。
J Cell Biol. 1986 Apr;102(4):1510-21. doi: 10.1083/jcb.102.4.1510.
7
Inhibition of surface membrane maturation in schistosomula of Schistosoma mansoni.
Proc Natl Acad Sci U S A. 1988 Jun;85(11):3825-9. doi: 10.1073/pnas.85.11.3825.
8
9
The unusual microtubule polarity in teleost retinal pigment epithelial cells.硬骨鱼视网膜色素上皮细胞中异常的微管极性。
J Cell Biol. 1988 Oct;107(4):1461-4. doi: 10.1083/jcb.107.4.1461.
10
The role of kinesin and other soluble factors in organelle movement along microtubules.驱动蛋白及其他可溶性因子在细胞器沿微管移动中的作用。
J Cell Biol. 1988 Nov;107(5):1785-92. doi: 10.1083/jcb.107.5.1785.
本文引用的文献
1
Chromatophores: their use in understanding microtubule-dependent intracellular transport.
Methods Cell Biol. 1982;25 Pt B:285-312. doi: 10.1016/s0091-679x(08)61430-2.
2
Structural interaction of cytoskeletal components.细胞骨架成分的结构相互作用。
J Cell Biol. 1981 Jul;90(1):222-35. doi: 10.1083/jcb.90.1.222.
3
Polarity of axoplasmic microtubules in the olfactory nerve of the frog.青蛙嗅神经中轴浆微管的极性
Proc Natl Acad Sci U S A. 1981 May;78(5):3269-73. doi: 10.1073/pnas.78.5.3269.
4
Localization of mitochondria in living cells with rhodamine 123.利用罗丹明123对活细胞中线粒体进行定位
Proc Natl Acad Sci U S A. 1980 Feb;77(2):990-4. doi: 10.1073/pnas.77.2.990.
5
Cytoplasmic transport: moving ultrastructural elements common to many cell types revealed by video-enhanced microscopy.
Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:85-7. doi: 10.1101/sqb.1982.046.01.012.
6
Polarity of some motility-related microtubules.一些与运动相关的微管的极性
Proc Natl Acad Sci U S A. 1981 Jan;78(1):372-6. doi: 10.1073/pnas.78.1.372.
7
Studies on the motility of the foraminifera. I. Ultrastructure of the reticulopodial network of Allogromia laticollaris (Arnold).有孔虫运动的研究。I. 宽颈全毛虫（阿诺德）网状伪足网络的超微结构。
J Cell Biol. 1981 Jul;90(1):211-21. doi: 10.1083/jcb.90.1.211.
8
Studies on the motility of the foraminifera. II. The dynamic microtubular cytoskeleton of the reticulopodial network of Allogromia laticollaris.有孔虫运动性的研究。II. 阔颈全裸阿米巴网状伪足网络的动态微管细胞骨架。
J Cell Biol. 1983 Dec;97(6):1668-76. doi: 10.1083/jcb.97.6.1668.
9
Cytoplasmic transport in keratocytes: direct visualization of particle translocation along microtubules.角膜细胞中的细胞质运输：沿微管的颗粒转运的直接可视化
Cell Motil. 1983;3(1):1-19. doi: 10.1002/cm.970030102.
10
Cytoplasmic dynein of the sea urchin egg. II. Purification, characterization and interactions with microtubules and Ca-calmodulin.海胆卵的细胞质动力蛋白。II. 纯化、特性鉴定及其与微管和钙调蛋白的相互作用
J Biochem. 1983 Jan;93(1):87-98. doi: 10.1093/oxfordjournals.jbchem.a134182.
Zotero 插件