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青少年缺铁时血红蛋白水平和红细胞参数的诊断准确性:一项横断面研究。

Diagnostic Accuracy of Hemoglobin Levels and Red Blood Cell Parameters for Iron Deficiency in Adolescents: A Cross-Sectional Study.

作者信息

Alsafi Walaa M, Gaffer Ahmed A, Al-Nafeesah Abdullah, AlEed Ashwaq, Alfaifi Jaber, Adam Ishag

机构信息

Gadarif University, El-Gadarif, Sudan.

Department of Pediatrics, College of Medicine, Qassim University, Buraydah, Saudi Arabia.

出版信息

Glob Pediatr Health. 2024 Dec 8;11:2333794X241304642. doi: 10.1177/2333794X241304642. eCollection 2024.

DOI:10.1177/2333794X241304642
PMID:39655001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11626664/
Abstract

. To assess the performance of hemoglobin level and red blood cell parameters (mean corpuscular volume [MCV], mean corpuscular hemoglobin [MCH], mean corpuscular hemoglobin concentration [MCHC], and red blood cell distribution width [RDW]) in the diagnosis of iron deficiency among adolescents in eastern Sudan. A cross-sectional study. Of 374 adolescents. The median age was 14.1 years. Of the participants, 62 (16.6%) had iron deficiency (serum ferritin level of < 15 µg/l). The hemoglobin, MCV, MCH, and MCHC values were significantly lower in adolescents with iron deficiency. The area under the receiver operating characteristic (ROC) curve was 0.71 for hemoglobin, 0.60 for MCV, 0.67 for MCH, 0.71 for MCHC, and 0.73 for RDW. In the current study, hemoglobin and red blood cell parameters were fairly accurate in diagnosing iron deficiency. They can be used to diagnose iron deficiency to avoid extra expense for the patients.

摘要

评估血红蛋白水平和红细胞参数(平均红细胞体积[MCV]、平均红细胞血红蛋白[MCH]、平均红细胞血红蛋白浓度[MCHC]和红细胞分布宽度[RDW])在苏丹东部青少年缺铁诊断中的表现。一项横断面研究。共374名青少年。中位年龄为14.1岁。参与者中,62人(16.6%)缺铁(血清铁蛋白水平<15μg/l)。缺铁青少年的血红蛋白、MCV、MCH和MCHC值显著更低。血红蛋白的受试者工作特征(ROC)曲线下面积为0.71,MCV为0.60,MCH为0.67,MCHC为0.71,RDW为0.73。在本研究中,血红蛋白和红细胞参数在诊断缺铁方面相当准确。它们可用于诊断缺铁,以避免患者产生额外费用。

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本文引用的文献

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Receiver operating characteristic curve analysis in diagnostic accuracy studies: A guide to interpreting the area under the curve value.诊断准确性研究中的受试者工作特征曲线分析:曲线下面积值解读指南。
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