Nassira Karich, Haloui Anass, Bekhakh Chaimae, Seghrouchni Noura, Bennani Amal
Pathology, Mohammed VI University International Hospital, Oujda, MAR.
Pathology, Faculty of Medicine, Mohammed VI University International Hospital, Mohamed I University, Oujda, MAR.
Cureus. 2024 Nov 9;16(11):e73312. doi: 10.7759/cureus.73312. eCollection 2024 Nov.
Secretory breast carcinoma (SBC) is a rare breast cancer subtype, histologically, defined by abundant eosinophilic secretions with a triple-negative staining on immunohistochemistry. The diagnosis is made histologically and often requires complementary methods such as immunohistochemical studies and fluorescence in situ hybridization (FISH). Surgery, whether conservative or radical, is the preferred treatment. The prognosis remains good. We report a case of a 46-year-old woman who presented with a right breast upper quadrant lump. She underwent a mastectomy with axillary curage. The pathological result was in favor of a breast secretory carcinoma. The lack of any poor prognostic factors allowed the patient to be placed on close follow-up with a good outcome and no recurrence or metastasis in the last two years.
分泌性乳腺癌(SBC)是一种罕见的乳腺癌亚型,在组织学上,其特征为富含嗜酸性分泌物,免疫组化呈三阴性染色。诊断依靠组织学检查,通常需要免疫组化研究和荧光原位杂交(FISH)等辅助方法。手术,无论是保乳手术还是根治性手术,都是首选的治疗方法。预后仍然良好。我们报告一例46岁女性患者,其右乳上象限出现肿块。她接受了乳房切除术及腋窝清扫术。病理结果支持乳腺分泌性癌的诊断。由于缺乏任何不良预后因素,该患者接受密切随访,结果良好,在过去两年中无复发或转移。