Lee Seung Geun, Jung Seung Pil, Lee Hye Yoon, Kim Sinill, Kim Hoon Yub, Kim Insun, Bae Jeoung Won
Breast Center, MD Hospital, Seoul, Republic of Korea.
Division of Breast and Endocrine Surgery, Department of Surgery, Korea University Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Oncol Lett. 2014 Aug;8(2):683-686. doi: 10.3892/ol.2014.2213. Epub 2014 Jun 3.
Secretory breast carcinoma is a very rare and distinct subtype of breast cancer, characterized by the presence of intracellular and extracellular secretory material. Secretory breast carcinoma has a good clinical outcome and systemic involvement is rare. The majority of studies of this tumor have been case reports or separate analyses, and due to the rarity of these tumors, it has been difficult to fully elucidate their characteristics and define optimal treatment strategies. To add to the current knowledge of secretory breast carcinoma, the present study reports three cases of secretory breast carcinoma in patients of different ages, and with different hormone receptor statuses and treatment methods. The present study identified that each patient with secretory breast carcinoma may present with different symptoms and clinical characteristics. Therefore, therapeutic options should be selected based on the overall status of the patient and the characteristics of this rare disease.
分泌性乳腺癌是一种非常罕见且独特的乳腺癌亚型,其特征是存在细胞内和细胞外分泌物质。分泌性乳腺癌的临床预后良好,很少发生全身转移。关于这种肿瘤的大多数研究都是病例报告或单独分析,由于这些肿瘤罕见,很难全面阐明其特征并确定最佳治疗策略。为了增加对分泌性乳腺癌的现有认识,本研究报告了三例不同年龄、不同激素受体状态和治疗方法的分泌性乳腺癌患者。本研究发现,每例分泌性乳腺癌患者可能表现出不同的症状和临床特征。因此,应根据患者的整体状况和这种罕见疾病的特征来选择治疗方案。