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成年女性尿道透明细胞腺癌：一例罕见病例报告。

Urethral clear cell adenocarcinoma in an adult female: A rare case report.

作者信息

Seman Yacob Sheiferawe, Abera Michael Teklehaimanot, Abrar Fadil Nuredin, Legesse Tesfaye Kebede, Tola Mesfin Asefa, Alemu Tsiyon Nigusie

机构信息

Addis Ababa University, College of Health Sciences, Department of Urology, Addis Ababa, Ethiopia.

Addis Ababa University, College of Health Sciences, Department of Radiology, Addis Ababa, Ethiopia.

出版信息

Urol Case Rep. 2024 Nov 13;58:102882. doi: 10.1016/j.eucr.2024.102882. eCollection 2025 Jan.

DOI:10.1016/j.eucr.2024.102882
PMID:39655199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11626717/
Abstract

Clear cell adenocarcinoma of the urethra is an extremely rare malignancy with a poor outcome, mainly affecting females in old age. We present the case of a 42-year-old female patient who presented with progressively worsening lower urinary tract symptoms, leading to a cystoscopy-guided core needle biopsy diagnosis of clear cell adenocarcinoma of the urethra. We will mainly discuss the cross-sectional imaging and pathological aspects of the case.

摘要

尿道透明细胞腺癌是一种极其罕见的恶性肿瘤，预后较差，主要影响老年女性。我们报告一例42岁女性患者，该患者出现进行性加重的下尿路症状，经膀胱镜引导下的芯针活检诊断为尿道透明细胞腺癌。我们将主要讨论该病例的横断面影像学和病理学方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/37af03314a84/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/e22c64a82c3b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/57902d268591/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/223fa06b540b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/89683a47d720/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/37af03314a84/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/e22c64a82c3b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/57902d268591/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/223fa06b540b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/89683a47d720/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbf6/11626717/37af03314a84/gr5.jpg

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本文引用的文献

1
Clear Cell Adenocarcinoma of Urethra: Clinical and Pathologic Implications and Characterization of Molecular Aberrations.尿道透明细胞腺癌：临床病理意义及分子异常特征。
Cancer Res Treat. 2024 Jan;56(1):280-293. doi: 10.4143/crt.2023.577. Epub 2023 Sep 11.
2
The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors.《2022 年世界卫生组织泌尿系统及男性生殖器官肿瘤分类-第 B 部分：前列腺和泌尿系统肿瘤》。
Eur Urol. 2022 Nov;82(5):469-482. doi: 10.1016/j.eururo.2022.07.002. Epub 2022 Aug 11.
3
European Association of Urology Guidelines on Primary Urethral Carcinoma-2020 Update.
欧洲泌尿外科学会原发性尿道癌指南-2020 更新版。
Eur Urol Oncol. 2020 Aug;3(4):424-432. doi: 10.1016/j.euo.2020.06.003. Epub 2020 Jun 27.
4
Outcomes and Prognostic Factors of Primary Urethral Cancer.原发性尿道癌的治疗结果及预后因素
Urology. 2017 Feb;100:180-186. doi: 10.1016/j.urology.2016.09.042. Epub 2016 Oct 5.
5
Clear cell adenocarcinoma of a female urethra: A case report and review of the literature.女性尿道透明细胞腺癌：一例报告并文献复习
N Am J Med Sci. 2009 Nov;1(6):321-3.
6
Primary clear cell adenocarcinoma of the bladder with recurrence: a case report and literature review.膀胱原发性透明细胞腺癌伴复发：病例报告及文献复习。
World J Surg Oncol. 2012 Feb 10;10:33. doi: 10.1186/1477-7819-10-33.
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Histogenesis of clear cell adenocarcinoma in the urinary tract: evidence of urothelial origin.泌尿道透明细胞腺癌的组织发生：尿路上皮起源的证据。
Clin Cancer Res. 2008 Apr 1;14(7):1947-55. doi: 10.1158/1078-0432.CCR-07-4147.
8
Cross-sectional imaging of the female urethra: technique and results.女性尿道的横断面成像：技术与结果
Radiographics. 2005 May-Jun;25(3):749-61. doi: 10.1148/rg.253045067.
9
Imaging of urethral disease: a pictorial review.尿道疾病的影像学：图文综述
Radiographics. 2004 Oct;24 Suppl 1:S195-216. doi: 10.1148/rg.24si045504.
10
MRI of female urethral and periurethral disorders.
AJR Am J Roentgenol. 2004 Mar;182(3):677-82. doi: 10.2214/ajr.182.3.1820677.