Acar Kasim, Karagiannidou Ariadni, Olsson Andreas, van Prooijen Jan-Willem, Balter Leonie J T, Axelsson John, Ingvar Martin, Lebedev Alexander V, Petrovic Predrag
Centre for Psychiatry Research (CPF), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Center for Cognitive and Computational Neuroscience (CCNP), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Front Psychiatry. 2024 Nov 25;15:1450429. doi: 10.3389/fpsyt.2024.1450429. eCollection 2024.
Vaccination-related conspiracy ideation is related to reduced compliance with public health advice globally. Such beliefs have previously been linked to the delusion-proneness trait. However, it is not known how this extends to getting vaccinated.
Here, we examined how delusion-proneness, as assessed by Peters et al. Delusions Inventory (PDI), is associated with COVID-19 vaccination in a sample of 273 subjects. We also examined whether delusion-proneness predicted the time to get vaccinated, after the vaccine became available.
Unvaccinated subjects were more delusion-prone than vaccinated subjects (W=2225.5, <0.001, =0.27). Among vaccinated subjects, higher delusion-proneness was related to longer time to get vaccinated ( =0.27, <0.001). These effects remained after adjusting for anxiety, ADHD, and ASD (Autism Spectrum Disorder) traits as well as for psychiatric diagnoses and sex. Path analyses indicated that the effect of delusion-proneness on vaccination rate was strongly mediated through COVID-19 conspiracy ideation, suggesting that delusion prone individuals first develop specific delusion-like ideas regarding vaccination, which then delays vaccination. An exploratory analysis of written text by subjects instructed to explain why they had vaccinated or not, revealed a difference in reasoning between the groups. Unvaccinated individuals were primarily motivated by concerns about personal safety and potential side effects, while vaccinated individuals stated a desire to protect themselves and others as the primary reasons to get vaccinated.
Our results suggest that delusion-proneness is a key factor for attaining conspiracy beliefs, at least in relation to COVID-19 pandemic, and associated with lower vaccination rates as well as longer time to get vaccinated.
与疫苗接种相关的阴谋论思维在全球范围内与对公共卫生建议的依从性降低有关。此前,此类信念与易产生妄想的特质有关。然而,尚不清楚这如何延伸至疫苗接种行为。
在此,我们在273名受试者的样本中研究了由彼得斯等人的妄想量表(PDI)评估的易产生妄想特质与新冠疫苗接种之间的关联。我们还研究了在疫苗可用后,易产生妄想特质是否能预测接种疫苗的时间。
未接种疫苗的受试者比接种疫苗的受试者更容易产生妄想(W = 2225.5,<0.001,r = 0.27)。在接种疫苗的受试者中,较高的易产生妄想特质与较长的接种时间相关(r = 0.27,<0.001)。在调整焦虑、注意力缺陷多动障碍和自闭症谱系障碍(ASD)特质以及精神疾病诊断和性别后,这些效应仍然存在。路径分析表明,易产生妄想特质对疫苗接种率的影响通过新冠阴谋论思维得到强烈介导,这表明易产生妄想的个体首先会形成关于疫苗接种的特定妄想样想法,进而延迟接种。对被要求解释为何接种或未接种疫苗的受试者书面文本的探索性分析揭示了两组之间在推理上的差异。未接种疫苗的个体主要出于对个人安全和潜在副作用的担忧,而接种疫苗的个体表示保护自己和他人的愿望是接种疫苗的主要原因。
我们的结果表明,易产生妄想特质是形成阴谋论信念的关键因素,至少在与新冠疫情相关方面如此,并且与较低的疫苗接种率以及较长的接种时间相关。