Nielsen Trine Muhs, Gils Charlotte, Nybo Mads
Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.
Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Clin Chem Lab Med. 2024 Dec 11;63(5):972-978. doi: 10.1515/cclm-2024-1018. Print 2025 Apr 28.
In the light of a rapidly increasing use of POCT blood gas testing, where tests and interpretation are performed by non-laboratory personnel, the objective was to investigate the knowledge among personnel in the Nordic countries using blood gas analyzers with focus on the interference from hemolysis.
Information was obtained from a self-developed, pre-tested online questionnaire. The questions covered demographic information about the respondents and specific questions on handling of and knowledge about blood gas analyses and the impact of hemolysis. The questionnaire was distributed by e-mail to relevant colleagues on behalf of the Nordic preanalytical scientific working group under the Nordic Federation of Clinical Chemistry.
A total of 117 respondents completed the questionnaire. 62.7 % respondents both used the analyzer and interpreted the results. 59.6 % respondents did not know to which degree the blood gas analyzer can identify hemolysis. 4.4 % answered that all levels or high levels of hemolysis can be detected. 3.9 % considered the result valid despite hemolysis if it is released from the instrument. 73.7 % of all respondents knew that hemolysis alters potassium measurements, while knowledge about the effect on PaO and bicarbonate measurements were more divergent.
The knowledge about blood gas analyzers with focus on the interference from hemolysis is sparse among non-laboratory personnel using the blood gas analyzers. This emphasizes the need for better education and competence management, which perhaps is even more important for these analyses than for other point-of-care tests.
鉴于即时检验（POCT）血气检测的使用迅速增加，且检测和结果解读由非实验室人员进行，本研究旨在调查北欧国家使用血气分析仪的人员对溶血干扰方面的知识掌握情况。
通过自行开发并预先测试的在线问卷获取信息。问题涵盖受访者的人口统计学信息以及关于血气分析操作、知识和溶血影响的具体问题。该问卷由北欧临床化学联合会下属的北欧分析前科学工作组通过电子邮件分发给相关同事。
共有117名受访者完成问卷。62.7%的受访者既使用分析仪又解读结果。59.6%的受访者不知道血气分析仪能识别溶血的程度。4.4%的受访者回答能检测到所有水平或高水平的溶血。3.9%的受访者认为如果仪器给出结果，即使存在溶血结果也是有效的。73.7%的受访者知道溶血会改变钾离子测量值，而关于溶血对氧分压（PaO）和碳酸氢根测量值影响的知识分歧较大。
在使用血气分析仪的非实验室人员中，对血气分析仪尤其是溶血干扰方面的知识掌握较为匮乏。这凸显了加强教育和能力管理的必要性，对于这些分析而言，这可能比其他即时检验更为重要。
