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逆行性肾内结石手术中吸引技术与非吸引技术的比较:一项系统评价和荟萃分析。

Comparison of suction technique and non-suction technique in retrograde intrarenal stone surgery: a systematic review and meta-analysis.

作者信息

Chen Pengan, Mi Gaoshen, Chen Jixiang, Liu Yu, Jian Zhongyu, Jin Xi, Wang Kunjie

机构信息

Department of Urology, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Int Urol Nephrol. 2025 Apr;57(4):1051-1062. doi: 10.1007/s11255-024-04280-6. Epub 2024 Dec 10.

Abstract

OBJECTIVE

To evaluate the clinical efficacy of retrograde intrarenal stone surgery (RIRS) using the vacuum suction technique for the treatment of upper urinary calculi.

METHODS

A comprehensive literature search was conducted across multiple databases, including PubMed, Embase, Sino Med, CNKI, WANFANG DATA, and Cochrane. We included studies comparing vacuum suction RIRS with non-vacuum RIRS. Following the PRISMA guidelines, we performed a meta-analysis of the selected studies. Inclusion criteria were randomized controlled trials (RCTs), case-control studies, and retrospective studies evaluating the efficacy of these techniques. Key outcomes analyzed included operative time, hospitalization duration, stone-free rates, and complication rates. Statistical analyses were conducted using mean differences (MD) for continuous variables and odds ratios (OR) for dichotomous outcomes, with corresponding 95% confidence intervals (CI).

RESULTS

Sixteen studies (6 RCTs, 1 case-control study, and 9 retrospective studies) involving a total of 2029 patients were included. Meta-analysis revealed that the vacuum suction technique significantly reduced operative time (MD = - 14.45 min, 95% CI [- 18.45; - 10.44], P < 0.00001) and hospital stay (MD = - 0.54 days, 95% CI [- 0.80; - 0.28], P < 0.00001). In addition, patients in the vacuum suction group had a higher stone-free rate (OR = 3.57, 95% CI [2.57; 4.95], P < 0.00001) and lower complication rates, particularly in reducing postoperative fever.

CONCLUSION

The application of the vacuum suction technique in RIRS significantly improves clinical outcomes by reducing operative time and hospitalization duration, enhancing stone-free rates, and lowering postoperative complication rates. This technique demonstrates a clear clinical advantage over non-vacuum RIRS and should be considered a preferred option for the management of upper urinary tract stones.

摘要

目的

评估采用真空抽吸技术的逆行性肾内结石手术(RIRS)治疗上尿路结石的临床疗效。

方法

在多个数据库中进行全面的文献检索,包括PubMed、Embase、中国生物医学文献数据库、中国知网、万方数据和Cochrane数据库。我们纳入了比较真空抽吸RIRS与非真空RIRS的研究。按照PRISMA指南,我们对所选研究进行了荟萃分析。纳入标准为评估这些技术疗效的随机对照试验(RCT)、病例对照研究和回顾性研究。分析的关键结局包括手术时间、住院时间、结石清除率和并发症发生率。连续变量采用均数差(MD),二分结局采用比值比(OR)进行统计分析,并给出相应的95%置信区间(CI)。

结果

共纳入16项研究(6项RCT、1项病例对照研究和9项回顾性研究),涉及2029例患者。荟萃分析显示,真空抽吸技术显著缩短了手术时间(MD = - 14.45分钟,95%CI[-18.45;-10.44],P < 0.00001)和住院时间(MD = - 0.54天,95%CI[-0.80;-0.28],P < 0.00001)。此外,真空抽吸组患者的结石清除率更高(OR = 3.57,95%CI[2.57;4.95],P < 0.00001),并发症发生率更低,尤其是术后发热的发生率降低。

结论

真空抽吸技术在RIRS中的应用通过缩短手术时间和住院时间、提高结石清除率以及降低术后并发症发生率,显著改善了临床结局。该技术相对于非真空RIRS具有明显的临床优势,应被视为治疗上尿路结石的首选方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53eb/11903590/274b62c210ed/11255_2024_4280_Fig1_HTML.jpg

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