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Ensembl 2025。

Ensembl 2025.

作者信息

Dyer Sarah C, Austine-Orimoloye Olanrewaju, Azov Andrey G, Barba Matthieu, Barnes If, Barrera-Enriquez Vianey Paola, Becker Arne, Bennett Ruth, Beracochea Martin, Berry Andrew, Bhai Jyothish, Bhurji Simarpreet Kaur, Boddu Sanjay, Branco Lins Paulo R, Brooks Lucy, Ramaraju Shashank Budhanuru, Campbell Lahcen I, Martinez Manuel Carbajo, Charkhchi Mehrnaz, Cortes Lucas A, Davidson Claire, Denni Sukanya, Dodiya Kamalkumar, Donaldson Sarah, El Houdaigui Bilal, El Naboulsi Tamara, Falola Oluwadamilare, Fatima Reham, Genez Thiago, Martinez Jose Gonzalez, Gurbich Tatiana, Hardy Matthew, Hollis Zoe, Hunt Toby, Kay Mike, Kaykala Vinay, Lemos Diana, Lodha Disha, Mathlouthi Nourhen, Merino Gabriela Alejandra, Merritt Ryan, Mirabueno Louisse Paola, Mushtaq Aleena, Hossain Syed Nakib, Pérez-Silva José G, Perry Malcolm, Piližota Ivana, Poppleton Daniel, Prosovetskaia Irina, Raj Shriya, Salam Ahamed Imran Abdul, Saraf Shradha, Saraiva-Agostinho Nuno, Sinha Swati, Sipos Botond, Sitnik Vasily, Steed Emily, Suner Marie-Marthe, Surapaneni Likhitha, Sutinen Kyösti, Tricomi Francesca Floriana, Tsang Ian, Urbina-Gómez David, Veidenberg Andres, Walsh Thomas A, Willhoft Natalie L, Allen Jamie, Alvarez-Jarreta Jorge, Chakiachvili Marc, Cheema Jitender, da Rocha Jorge Batista, De Silva Nishadi H, Giorgetti Stefano, Haggerty Leanne, Ilsley Garth R, Keatley Jon, Loveland Jane E, Moore Benjamin, Mudge Jonathan M, Naamati Guy, Tate John, Trevanion Stephen J, Winterbottom Andrea, Flint Bethany, Frankish Adam, Hunt Sarah E, Finn Robert D, Freeberg Mallory A, Harrison Peter W, Martin Fergal J, Yates Andrew D

机构信息

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

Université de Rouen Normandie, UFR Sciences et Techniques, 3 Av. Pasteur, 76000 Rouen, France.

出版信息

Nucleic Acids Res. 2025 Jan 6;53(D1):D948-D957. doi: 10.1093/nar/gkae1071.

DOI:10.1093/nar/gkae1071
PMID:39656687
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11701638/
Abstract

Ensembl (www.ensembl.org) is an open platform integrating publicly available genomics data across the tree of life with a focus on eukaryotic species related to human health, agriculture and biodiversity. This year has seen a continued expansion in the number of species represented, with >4800 eukaryotic and >31 300 prokaryotic genomes available. The new Ensembl site, currently in beta, has continued to develop, currently holding >2700 eukaryotic genome assemblies. The new site provides genome, gene, transcript, homology and variation views, and will replace the current Rapid Release site; this represents a key step towards provision of a single integrated Ensembl site. Additional activities have included developing improved regulatory annotation for human, mouse and agricultural species, and expanding the Ensembl Variant Effect Predictor tool. To learn more about Ensembl, help and documentation are available along with an extensive training program that can be accessed via our training pages.

摘要

Ensembl(www.ensembl.org)是一个开放平台,整合了整个生命之树中公开可用的基因组学数据,重点关注与人类健康、农业和生物多样性相关的真核生物物种。今年,所涵盖的物种数量持续增加,现有超过4800个真核生物基因组和超过31300个原核生物基因组。目前处于测试阶段的新Ensembl网站持续发展,目前拥有超过2700个真核生物基因组组装。新网站提供基因组、基因、转录本、同源性和变异视图,并将取代当前的快速发布网站;这是迈向提供单一集成Ensembl网站的关键一步。其他活动包括为人类、小鼠和农业物种开发改进的调控注释,以及扩展Ensembl变异效应预测工具。要了解有关Ensembl的更多信息,可以获取帮助和文档,以及可通过我们的培训页面访问的广泛培训计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/30b139dd4df3/gkae1071fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/d94987cf1aa9/gkae1071figgra1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/ff3a4357a8f7/gkae1071fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/d0abcb110e6d/gkae1071fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/30b139dd4df3/gkae1071fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/d94987cf1aa9/gkae1071figgra1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/ff3a4357a8f7/gkae1071fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/d0abcb110e6d/gkae1071fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bae2/11701638/30b139dd4df3/gkae1071fig3.jpg

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