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2022年9月至2023年4月美国6个月至4岁儿童接种新冠病毒疫苗及既往感染新冠病毒后的防护情况

Protection From COVID-19 Vaccination and Prior SARS-CoV-2 Infection Among Children Aged 6 Months-4 Years, United States, September 2022-April 2023.

作者信息

Feldstein Leora R, Ruffin Jasmine, Wiegand Ryan, Grant Lauren, Babu Tara M, Briggs-Hagen Melissa, Burgess Jefferey L, Caban-Martinez Alberto J, Chu Helen Y, Ellingson Katherine D, Englund Janet A, Hegmann Kurt T, Jeddy Zuha, Kuntz Jennifer, Lauring Adam S, Lutrick Karen, Martin Emily T, Mathenge Clare, Meece Jennifer, Midgley Claire M, Monto Arnold S, Naleway Allison L, Newes-Adeyi Gabriella, Odame-Bamfo Leah, Olsho Lauren E W, Phillips Andrew L, Rai Ramona P, Saydah Sharon, Smith Ning, Tyner Harmony, Vaughan Molly, Weil Ana A, Yoon Sarang K, Britton Amadea, Gaglani Manjusha

机构信息

Coronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

出版信息

J Pediatric Infect Dis Soc. 2025 Jan 20;14(1). doi: 10.1093/jpids/piae121.

Abstract

To understand how coronavirus disease 2019 vaccines impact infection risk in children <5 years, we assessed risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection from September 2022 to April 2023 in 3 cohort studies. There was no difference in risk by vaccination status. While vaccines reduce severe disease, they may not reduce SARS-CoV-2 infections in naïve young children.

摘要

为了解2019冠状病毒病疫苗如何影响5岁以下儿童的感染风险,我们在3项队列研究中评估了2022年9月至2023年4月期间严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的感染风险。接种疫苗状况对感染风险没有影响。虽然疫苗可降低重症疾病的发生,但可能无法减少未接种疫苗的幼儿感染SARS-CoV-2。

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