Ghasad Preeti P, Vegivada Jagath V S, Kamble Vipin M, Bhurane Ankit A, Santosh Nikhil, Sharma Manish, Tan Ru-San, Rajendra Acharya U
Department of Electronics and Communication Engineering, Visvesvaraya National Institute of Technology, Nagpur 440010, Maharashtra, India.
Department of Electrical and Computer Science Engineering, Institute of Infrastructure Technology Research and Management, Ahmedabad 380026, Gujarat, India.
Physiol Meas. 2025 Jan 23;13(1). doi: 10.1088/1361-6579/ad9ce5.
. Sudden cardiac death (SCD) stands as a life-threatening cardiac event capable of swiftly claiming lives. It ranks prominently among the leading causes of global mortality, contributing to approximately 10% of deaths worldwide. The timely anticipation of SCD holds the promise of immediate life-saving interventions, such as cardiopulmonary resuscitation. However, recent strides in the realms of deep learning (DL), machine learning (ML), and artificial intelligence have ushered in fresh opportunities for the automation of SCD prediction using physiological signals. Researchers have devised numerous models to automatically predict SCD using a combination of diverse feature extraction techniques and classifiers. Methods: We conducted a thorough review of research publications ranging from 2011 to 2023, with a specific focus on the automated prediction of SCD. Traditionally, specialists utilize molecular biomarkers, symptoms, and 12-lead ECG recordings for SCD prediction. However, continuous patient monitoring by experts is impractical, and only a fraction of patients seeks help after experiencing symptoms. However, over the past two decades, ML techniques have emerged and evolved for this purpose. Importantly, since 2021, the studies we have scrutinized delve into a diverse array of ML and DL algorithms, encompassing K-nearest neighbors, support vector machines, decision trees, random forest, Naive Bayes, and convolutional neural networks as classifiers.. This literature review presents a comprehensive analysis of ML and DL models employed in predicting SCD. The analysis provided valuable information on the fundamental structure of cardiac fatalities, extracting relevant characteristics from electrocardiogram (ECG) and heart rate variability (HRV) signals, using databases, and evaluating classifier performance. The review offers a succinct yet thorough examination of automated SCD prediction methodologies, emphasizing current constraints and underscoring the necessity for further advancements. It serves as a valuable resource, providing valuable insights and outlining potential research directions for aspiring scholars in the domain of SCD prediction.. In recent years, researchers have made substantial strides in the prediction of SCD by leveraging openly accessible databases such as the MIT-BIH SCD Holter and Normal Sinus Rhythm, which contains extensive 24 h recordings of SCD patients. These sophisticated methodologies have previously demonstrated the potential to achieve remarkable accuracy, reaching levels as high as 97%, and can forecast SCD events with a lead time of 30-70 min. Despite these promising outcomes, the quest for even greater accuracy and reliability persists. ML and DL methodologies have shown great promise, their performance is intrinsically linked to the volume of training data available. Most predictive models rely on small-scale databases, raising concerns about their applicability in real-world scenarios. Furthermore, these models predominantly utilize ECG and HRV signals, often overlooking the potential contributions of other physiological signals. Developing real-time, clinically applicable models also represents a critical avenue for further exploration in this field.
心脏性猝死(SCD)是一种危及生命的心脏事件,能够迅速夺走生命。它在全球主要死因中占据显著地位,约占全球死亡人数的10%。及时预测SCD有望立即采取挽救生命的干预措施,如心肺复苏。然而,深度学习(DL)、机器学习(ML)和人工智能领域的最新进展为利用生理信号实现SCD预测自动化带来了新机遇。研究人员设计了众多模型,通过结合多种特征提取技术和分类器来自动预测SCD。方法:我们对2011年至2023年的研究出版物进行了全面回顾,特别关注SCD的自动化预测。传统上,专家利用分子生物标志物、症状和12导联心电图记录来预测SCD。然而,由专家进行持续的患者监测并不实际,而且只有一小部分患者在出现症状后寻求帮助。然而,在过去二十年中,ML技术已为此目的出现并不断发展。重要的是,自2021年以来,我们审查的研究深入探讨了各种ML和DL算法,包括作为分类器的K近邻、支持向量机、决策树、随机森林、朴素贝叶斯和卷积神经网络。这篇文献综述对用于预测SCD的ML和DL模型进行了全面分析。该分析提供了有关心脏死亡基本结构的有价值信息,从心电图(ECG)和心率变异性(HRV)信号中提取相关特征,使用数据库,并评估分类器性能。该综述对自动化SCD预测方法进行了简洁而全面的审视,强调了当前的限制并突出了进一步改进的必要性。它是一个有价值的资源,为SCD预测领域有抱负的学者提供了有价值的见解并概述了潜在的研究方向。近年来,研究人员通过利用公开可用的数据库,如麻省理工学院 - 贝斯以色列女执事医疗中心(MIT - BIH)SCD动态心电图和正常窦性心律数据库,在SCD预测方面取得了重大进展,该数据库包含SCD患者广泛的24小时记录。这些先进方法此前已证明有可能实现高达97%的显著准确率,并能提前30 - 70分钟预测SCD事件。尽管取得了这些有希望的成果,但对更高准确性和可靠性的追求仍在继续。ML和DL方法显示出巨大潜力,但其性能与可用训练数据的量内在相关。大多数预测模型依赖于小规模数据库,这引发了对其在现实场景中适用性的担忧。此外,这些模型主要利用ECG和HRV信号,常常忽略了其他生理信号的潜在贡献。开发实时、临床适用的模型也是该领域进一步探索的关键途径。
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