Jiu J B, Sobol S M, Grozea P N
Laryngoscope. 1985 Jan;95(1):57-9. doi: 10.1288/00005537-198501000-00013.
Vocal cord paralysis has been reported in 33 patients with thyroid lymphoma for an estimated overall incidence of 17%. There is little expectation of vocal cord function recovery, both because neoplastic invasion is believed irreversible and since surgery often necessitates sacrifice of the recurrent laryngeal nerve. Unlike in most well differentiated thyroid malignancies, external radiation therapy plays a vital role in the treatment of thyroid lymphoma. The patient presented here had complete recovery of vocal cord function following radiation therapy for a large thyroid lymphoma associated with vocal cord paralysis. This is the first reported case of such recovery following treatment for a thyroid neoplasm. The rather rapid and complete recovery of neural function suggests that, at least in some, paralysis is caused by reversible compression rather than by neural invasion or tumor-induced neurolysis.
据报道，33例甲状腺淋巴瘤患者出现声带麻痹，估计总体发生率为17%。声带功能恢复的希望渺茫，这既是因为肿瘤侵犯被认为是不可逆的，也是因为手术常常需要牺牲喉返神经。与大多数高分化甲状腺恶性肿瘤不同，外照射放疗在甲状腺淋巴瘤的治疗中起着至关重要的作用。本文介绍的患者在接受放疗后，与声带麻痹相关的巨大甲状腺淋巴瘤导致的声带功能完全恢复。这是甲状腺肿瘤治疗后出现这种恢复情况的首例报道病例。神经功能相当迅速且完全的恢复表明，至少在某些情况下，麻痹是由可逆性压迫而非神经侵犯或肿瘤诱导的神经溶解引起的。
