血液透析与持续性非卧床腹膜透析患者获得性囊性肾病的比较。

Comparison of acquired cystic kidney disease between hemodialysis and continuous ambulatory peritoneal dialysis.

作者信息

Park J H, Kim Y O, Park J H, Kim B S, Yoon S A, Yang C W, Kim Y S, Han C H, Kim B S, Bang B K

机构信息

Department of Internal Medicine, Catholic University of Korea, Seoul, Korea.

出版信息

Korean J Intern Med. 2000 Jan;15(1):51-5. doi: 10.3904/kjim.2000.15.1.51.

DOI:10.3904/kjim.2000.15.1.51

PMID:10714092

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4531734/

Abstract

OBJECTIVES

ACKD has been described mainly in patients treated with hemodialysis(HD), and there are only a few reports about the prevalence of ACKD in continuous ambulatory peritoneal dialysis (CAPD) patients. Therefore, we compared the prevalence of ACKD in patients receiving HD and CAPD, and evaluated the possible factors which may affect the development of ACKD.

METHODS

Forty nine HD and 49 CAPD patients who had received dialysis therapy for at least 12 months were enrolled in this cross-sectional study. Patients who had a past history of polycystic kidney disease and had acquired cystic kidney disease on predialysis sonographic exam were excluded. Detection of ACKD was made by ultrasonography and ACKD was defined as 3 or more cysts in each kidney.

RESULTS

The prevalence of ACKD was about 31% (30/98) and there was no significant difference between HD and CAPD patients(27% vs. 34%, p > 0.05). The prevalence of ACKD was not associated with age, sex, primary renal disease, the levels of hemoglobin, BUN, and serum creatinine. However, the duration of dialysis was significantly related to the development of ACKD (presence of ACKD, 74.4 +/- 42.4 months vs. absence of ACKD, 37.8 +/- 24.1 months, p < 0.05).

CONCLUSION

The prevalence of ACKD is not different according to the mode of dialysis, and the major determinant of acquired cyst formation is duration of dialysis.

摘要

目的

获得性肾囊肿疾病（ACKD）主要在接受血液透析（HD）的患者中被描述，而关于持续非卧床腹膜透析（CAPD）患者中ACKD患病率的报道较少。因此，我们比较了接受HD和CAPD患者中ACKD的患病率，并评估了可能影响ACKD发生的因素。

方法

本横断面研究纳入了49例接受HD和49例接受CAPD且透析治疗至少12个月的患者。排除有多囊肾病史以及透析前超声检查发现获得性肾囊肿疾病的患者。通过超声检查检测ACKD，ACKD定义为每个肾脏有3个或更多囊肿。

结果

ACKD的患病率约为31%（30/98），HD和CAPD患者之间无显著差异（27%对34%，p>0.05）。ACKD的患病率与年龄、性别、原发性肾脏疾病、血红蛋白、尿素氮和血清肌酐水平无关。然而，透析时间与ACKD的发生显著相关（存在ACKD者，74.4±42.4个月对不存在ACKD者，37.8±24.1个月，p<0.05）。