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Quantification of the FLT3 internal tandem duplication is a reliable marker for monitoring measurable residual disease in acute myeloid leukemia with FLT3-ITD mutations.

作者信息

Wang Meng-Miao, Huang Si-Man, Huang Yuan-Hong, Zhang Jian, Li Hui-Ying, Ge Shuai-Shuai, Wan Chao-Ling, Wang Miao, Liu Hai-Hui, Cao Han-Yu, Wang Zi-Hao, Tan Kai-Wen, Pang Hong-Feng, Lyu Xiao-Yu, Liu Song-Bai, Dai Hai-Ping, Xue Sheng-Li, Qiu Qiao-Cheng

机构信息

Department of Hematology, Qinghai Provincial People's Hospital, Xining, China.

National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.

出版信息

Bone Marrow Transplant. 2025 Mar;60(3):412-414. doi: 10.1038/s41409-024-02495-w. Epub 2024 Dec 10.

DOI:10.1038/s41409-024-02495-w
PMID:39658655
Abstract
摘要

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DNA Sequencing in Adults With Acute Myeloid Leukemia to Detect Residual Disease Prior to Hematopoietic Cell Transplant.对成人急性髓系白血病患者进行DNA测序以在造血细胞移植前检测残留疾病。
JAMA. 2023 Jul 11;330(2):190. doi: 10.1001/jama.2023.8650.
2
-ITD Measurable Residual Disease Monitoring in Acute Myeloid Leukemia Using Next-Generation Sequencing.使用下一代测序技术监测急性髓系白血病中可测量的内部串联重复突变残留疾病
Cancers (Basel). 2022 Dec 12;14(24):6121. doi: 10.3390/cancers14246121.
3
Prognostic Value of -Internal Tandem Duplication Residual Disease in Acute Myeloid Leukemia.
急性髓系白血病中-串联重复残留病的预后价值。
J Clin Oncol. 2023 Feb 1;41(4):756-765. doi: 10.1200/JCO.22.00715. Epub 2022 Oct 31.
4
Pretransplant FLT3-ITD MRD assessed by high-sensitivity PCR-NGS determines posttransplant clinical outcome.通过高灵敏度聚合酶链反应-下一代测序评估的移植前FLT3-ITD微小残留病可确定移植后的临床结局。
Blood. 2022 Dec 1;140(22):2407-2411. doi: 10.1182/blood.2022016567.
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Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.成人 AML 的诊断与治疗：ELN 专家组代表发布的 2022 年国际专家建议
Blood. 2022 Sep 22;140(12):1345-1377. doi: 10.1182/blood.2022016867.
6
A review of FLT3 inhibitors in acute myeloid leukemia.FLT3 抑制剂在急性髓系白血病中的研究进展。
Blood Rev. 2022 Mar;52:100905. doi: 10.1016/j.blre.2021.100905. Epub 2021 Nov 3.
7
2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party.2021 年急性髓系白血病微小残留病更新：来自欧洲白血病网微小残留病工作组的共识文件。
Blood. 2021 Dec 30;138(26):2753-2767. doi: 10.1182/blood.2021013626.
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