Unlu Metin, Ozer Furkan, Vural Alperen
Department of Ophthalmology, Division of Oculoplastic, Orbital, and Lacrimal Surgery, Erciyes University Medical Faculty, Kayseri, Türkiye.
Sungurlu State Hospital, Corum, Türkiye.
Int Ophthalmol. 2024 Dec 10;45(1):6. doi: 10.1007/s10792-024-03379-0.
To compare the results of one-step surgery (OSS) and two-step surgery (TSS) in the surgical management of eyelid basal cell carcinomas (BCC).
A total of 43 eyes of 43 patients were included. OSS was applied to 22 of these patients, while TSS was applied to 21 patients. The safety margin width (SMW), the size and location of the tumor, the histopathology results, and the reconstructive procedures were compared.
Resected tumor sizes were significantly larger in the TSS group than in the OSS group (largest tumor diameter: p = 0.005 and perpendicular diameter to largest diameter: p = 0.01). Excised SMW was higher in the OSS group compared to the TSS group (p = 0.008). A positive histopathological margin was observed in 2 patients (9%) in the TSS group and in 5 patients (22%) in the OSS group (p = 0.241). In addition, excision status including the nasolacrimal drainage system (NLDS) components was present in 4 patients (18%) in OSS group and 6 patients (28%) in TSS group (p = 0.42). While monocanalicular tube intubation could be performed in all TSS patients, it could only be performed in 1 patient in the OSS group (p = 0.03). The total number of reconstructive procedures performed was similar between groups (p = 0.058).
With regard to recurrence and metastasis, both OSS and TSS demonstrated success in the present study. This success was achieved in larger eyelid BCC tumors using the TSS technique with smaller amounts of SMW and in smaller eyelid BCC tumors using the OSS technique with larger amounts of SMW.
比较一步手术(OSS)和两步手术(TSS)在眼睑基底细胞癌(BCC)手术治疗中的效果。
纳入43例患者的43只眼。其中22例患者采用OSS,21例患者采用TSS。比较安全切缘宽度(SMW)、肿瘤大小和位置、组织病理学结果及重建手术。
TSS组切除的肿瘤大小显著大于OSS组(最大肿瘤直径:p = 0.005;与最大直径垂直的直径:p = 0.01)。OSS组切除的SMW高于TSS组(p = 0.008)。TSS组2例患者(9%)和OSS组5例患者(22%)观察到组织病理学切缘阳性(p = 0.241)。此外,OSS组4例患者(18%)和TSS组6例患者(28%)的切除范围包括鼻泪引流系统(NLDS)组件(p = 0.42)。虽然所有TSS患者均可进行单泪小管插管,但OSS组仅1例患者可行(p = 0.03)。两组进行的重建手术总数相似(p = 0.058)。
关于复发和转移,本研究中OSS和TSS均显示成功。使用TSS技术在较大的眼睑BCC肿瘤中以较小的SMW量取得了这种成功,而使用OSS技术在较小的眼睑BCC肿瘤中以较大的SMW量取得了成功。