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两种眼睑基底细胞癌手术技术的比较:两步手术与一步手术。

A comparison of two surgical techniques for basal cell carcinoma of the eyelid: two-step surgery and one-step surgery.

作者信息

Unlu Metin, Ozer Furkan, Vural Alperen

机构信息

Department of Ophthalmology, Division of Oculoplastic, Orbital, and Lacrimal Surgery, Erciyes University Medical Faculty, Kayseri, Türkiye.

Sungurlu State Hospital, Corum, Türkiye.

出版信息

Int Ophthalmol. 2024 Dec 10;45(1):6. doi: 10.1007/s10792-024-03379-0.

DOI:10.1007/s10792-024-03379-0
PMID:39658691
Abstract

OBJECTIVE

To compare the results of one-step surgery (OSS) and two-step surgery (TSS) in the surgical management of eyelid basal cell carcinomas (BCC).

METHOD

A total of 43 eyes of 43 patients were included. OSS was applied to 22 of these patients, while TSS was applied to 21 patients. The safety margin width (SMW), the size and location of the tumor, the histopathology results, and the reconstructive procedures were compared.

RESULTS

Resected tumor sizes were significantly larger in the TSS group than in the OSS group (largest tumor diameter: p = 0.005 and perpendicular diameter to largest diameter: p = 0.01). Excised SMW was higher in the OSS group compared to the TSS group (p = 0.008). A positive histopathological margin was observed in 2 patients (9%) in the TSS group and in 5 patients (22%) in the OSS group (p = 0.241). In addition, excision status including the nasolacrimal drainage system (NLDS) components was present in 4 patients (18%) in OSS group and 6 patients (28%) in TSS group (p = 0.42). While monocanalicular tube intubation could be performed in all TSS patients, it could only be performed in 1 patient in the OSS group (p = 0.03). The total number of reconstructive procedures performed was similar between groups (p = 0.058).

CONCLUSION

With regard to recurrence and metastasis, both OSS and TSS demonstrated success in the present study. This success was achieved in larger eyelid BCC tumors using the TSS technique with smaller amounts of SMW and in smaller eyelid BCC tumors using the OSS technique with larger amounts of SMW.

摘要

目的

比较一步手术(OSS)和两步手术(TSS)在眼睑基底细胞癌(BCC)手术治疗中的效果。

方法

纳入43例患者的43只眼。其中22例患者采用OSS,21例患者采用TSS。比较安全切缘宽度(SMW)、肿瘤大小和位置、组织病理学结果及重建手术。

结果

TSS组切除的肿瘤大小显著大于OSS组(最大肿瘤直径:p = 0.005;与最大直径垂直的直径:p = 0.01)。OSS组切除的SMW高于TSS组(p = 0.008)。TSS组2例患者(9%)和OSS组5例患者(22%)观察到组织病理学切缘阳性(p = 0.241)。此外,OSS组4例患者(18%)和TSS组6例患者(28%)的切除范围包括鼻泪引流系统(NLDS)组件(p = 0.42)。虽然所有TSS患者均可进行单泪小管插管,但OSS组仅1例患者可行(p = 0.03)。两组进行的重建手术总数相似(p = 0.058)。

结论

关于复发和转移,本研究中OSS和TSS均显示成功。使用TSS技术在较大的眼睑BCC肿瘤中以较小的SMW量取得了这种成功,而使用OSS技术在较小的眼睑BCC肿瘤中以较大的SMW量取得了成功。

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本文引用的文献

1
Retrospective evaluation of the utility of two-step surgery for facial basal cell carcinoma and squamous cell carcinoma.面部基底细胞癌和鳞状细胞癌两步手术效用的回顾性评估。
Front Surg. 2022 Sep 7;9:915731. doi: 10.3389/fsurg.2022.915731. eCollection 2022.
2
Periocular basal cell carcinoma results and surgical outcome during a 5-year period in a larger Danish population.5 年内丹麦较大人群中眼周基底细胞癌的结果和手术结局。
BMC Ophthalmol. 2022 Jun 28;22(1):282. doi: 10.1186/s12886-022-02494-9.
3
[Surgical resection with ophthalmoplastic reconstruction : Gold standard in periocular basal cell carcinoma].
[手术切除联合眼整形重建:眼周基底细胞癌的金标准]
Ophthalmologe. 2020 Feb;117(2):95-105. doi: 10.1007/s00347-019-00973-x.
4
Dermoscopy Patterns and Histopathological Findings in Nodular Basal Cell Carcinoma-Study on 68 Cases.结节性基底细胞癌的皮肤镜模式与组织病理学发现——68例研究
Curr Health Sci J. 2019 Jan-Mar;45(1):116-122. doi: 10.12865/CHSJ.45.01.16. Epub 2019 Mar 31.
5
Diagnosis and treatment of basal cell carcinoma: European consensus-based interdisciplinary guidelines.基底细胞癌的诊断和治疗:基于欧洲共识的跨学科指南。
Eur J Cancer. 2019 Sep;118:10-34. doi: 10.1016/j.ejca.2019.06.003. Epub 2019 Jul 6.
6
[Techniques for the Reconstruction of the Posterior Eyelid Lamella].[后睑板重建技术]
Klin Monbl Augenheilkd. 2018 Dec;235(12):1415-1428. doi: 10.1055/a-0751-1069. Epub 2018 Nov 23.
7
Cancer statistics, 2016.癌症统计数据,2016 年。
CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30. doi: 10.3322/caac.21332. Epub 2016 Jan 7.
8
Trends in Basal Cell Carcinoma Incidence and Identification of High-Risk Subgroups, 1998-2012.1998-2012 年基底细胞癌发病率趋势及高危亚组鉴定。
JAMA Dermatol. 2015 Sep;151(9):976-81. doi: 10.1001/jamadermatol.2015.1188.
9
Dermoscopic features in different morphologic types of basal cell carcinoma.不同形态学类型基底细胞癌的皮肤镜特征。
Dermatol Surg. 2014 Jul;40(7):725-32. doi: 10.1111/dsu.0000000000000034.
10
Eyelid and periorbital skin basal cell carcinoma: oculoplastic management and surgery.眼睑及眶周皮肤基底细胞癌:眼整形治疗与手术
Int Ophthalmol Clin. 2009 Fall;49(4):1-16. doi: 10.1097/IIO.0b013e3181b7ebe8.