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Racial and Ethnic Disease Phenotype Differences Are Driven by Genetics: Commentary.

作者信息

Munger Kathleen C, Rotstein Dalia L

机构信息

MultiCare Neuroscience & Sleep Medicine, Tacoma, Washington, USA.

University of Toronto, Department of Medicine, Toronto, ON, Canada; St. Michael's Hospital, Toronto, ON, Canada.

出版信息

Mult Scler. 2024 Dec;30(5_suppl):11-12. doi: 10.1177/13524585241301304.

DOI:10.1177/13524585241301304
PMID:39658903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11633066/
Abstract
摘要

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Nature. 2023 Jul;619(7969):323-331. doi: 10.1038/s41586-023-06250-x. Epub 2023 Jun 28.
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Genetic susceptibility to multiple sclerosis in African Americans.非裔美国人多发性硬化症的遗传易感性。
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HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis.HLA-DR15 分子共同塑造多发性硬化症中的自身反应性 T 细胞库。
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Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry.混合映射揭示了遗传背景对多发性硬化症风险的差异影响。
PLoS Genet. 2019 Jan 17;15(1):e1007808. doi: 10.1371/journal.pgen.1007808. eCollection 2019 Jan.
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Memory B Cells Activate Brain-Homing, Autoreactive CD4 T Cells in Multiple Sclerosis.记忆 B 细胞在多发性硬化症中激活归巢至脑、自身反应性 CD4 T 细胞。
Cell. 2018 Sep 20;175(1):85-100.e23. doi: 10.1016/j.cell.2018.08.011. Epub 2018 Aug 30.
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Structural racism and health inequities in the USA: evidence and interventions.美国的结构性种族主义和健康不平等：证据与干预。
Lancet. 2017 Apr 8;389(10077):1453-1463. doi: 10.1016/S0140-6736(17)30569-X.
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Childhood obesity and risk of pediatric multiple sclerosis and clinically isolated syndrome.儿童肥胖与小儿多发性硬化症和临床孤立综合征的风险。
Neurology. 2013 Feb 5;80(6):548-52. doi: 10.1212/WNL.0b013e31828154f3. Epub 2013 Jan 30.
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Discrimination-related stress, blood pressure and epstein-barr virus antibodies among latin american immigrants in Oregon, us.美国俄勒冈州拉丁裔移民的歧视相关压力、血压和爱泼斯坦-巴尔病毒抗体。
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