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心脏血管肉瘤:多模态成像和准分子激光辅助心内活检如何促成正确诊断——病例报告

Cardiac angiosarcoma: how multimodality imaging and excimer laser assisted intracardiac biopsy led to the correct diagnosis-a case report.

作者信息

Veliqi Anna, Hakmi Samer, Kaiser Lukas, Willems Stephan, Chung Da-Un

机构信息

Department of Cardiology & Critical Care Medicine, Asklepios Klinik St. Georg, Lohmühlenstraße 5, 20099 Hamburg, Germany.

Department of Cardiac Surgery, Asklepios Klinik St. Georg, Lohmühlenstraße 5, 20099 Hamburg, Germany.

出版信息

Eur Heart J Case Rep. 2024 Aug 24;8(12):ytae433. doi: 10.1093/ehjcr/ytae433. eCollection 2024 Dec.

DOI:10.1093/ehjcr/ytae433
PMID:39659466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11630895/
Abstract

BACKGROUND

Cardiac angiosarcomas are exceptionally uncommon, and result in significant morbidity and mortality. Utilizing a multimodality approach enhances the characterization of the mass for optimal diagnostic outcomes. The recommended primary treatment involves complete surgical resection coupled with adjuvant radiochemotherapy. Excimer laser sheaths provide a novel option for extracting substantial tissue samples, facilitating appropriate and targeted treatment.

CASE SUMMARY

A 54-year-old female presented with dyspnoea and chest pain. Cardiac imaging showed a large right atrial mass suspected to be malignant. Echocardiography was utilized for diagnosis, follow-ups, and as part of the biopsy procedure. However, adopting an off-label approach involving an excimer laser sheath as a bioptome led to the successful diagnosis of an angiosarcoma. Commencement of radiochemotherapy resulted in a reduction in tumour size and a rapid improvement in the patient's quality of life.

DISCUSSION

The presented case underlines the significance of multimodality imaging and the use of an excimer laser-assisted intracardiac biopsy in achieving an accurate diagnosis. Cardiovascular imaging not only serves as the primary diagnostic tool but also plays a crucial role in risk stratification and in planning therapeutic interventions.

摘要

背景

心脏血管肉瘤极为罕见,会导致严重的发病率和死亡率。采用多模态方法可增强对肿块的特征描述,以实现最佳诊断结果。推荐的主要治疗方法包括完整的手术切除以及辅助放化疗。准分子激光鞘为获取大量组织样本提供了一种新选择,有助于进行适当且有针对性的治疗。

病例摘要

一名54岁女性出现呼吸困难和胸痛。心脏成像显示右心房有一个大肿块,怀疑为恶性。超声心动图用于诊断、随访以及活检过程的一部分。然而,采用一种涉及将准分子激光鞘用作活检刀的非标签方法成功诊断出血管肉瘤。开始放化疗后,肿瘤大小减小,患者生活质量迅速改善。

讨论

该病例强调了多模态成像以及使用准分子激光辅助心内活检以实现准确诊断的重要性。心血管成像不仅是主要诊断工具,而且在风险分层和规划治疗干预方面也起着关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/61b9353f48f2/ytae433f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/77ce79a50107/ytae433il2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/395b33116fde/ytae433f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/ea0d348a3b01/ytae433f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/2fcf19363632/ytae433f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/61b9353f48f2/ytae433f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/77ce79a50107/ytae433il2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/395b33116fde/ytae433f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/ea0d348a3b01/ytae433f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/2fcf19363632/ytae433f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdab/11630895/61b9353f48f2/ytae433f4.jpg

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本文引用的文献

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Clin Transl Radiat Oncol. 2023 Mar 22;40:100619. doi: 10.1016/j.ctro.2023.100619. eCollection 2023 May.
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Think outside the box: a case report of utilization of an excimer laser sheath as an intracardiac bioptome.跳出框框思考:使用准分子激光鞘作为心内活检钳的病例报告。
Eur Heart J Case Rep. 2023 Feb 27;7(3):ytad107. doi: 10.1093/ehjcr/ytad107. eCollection 2023 Mar.
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Surgical treatment of primary cardiac tumors in the contemporary era: A single-centre analysis.
当代原发性心脏肿瘤的外科治疗:单中心分析。
J Card Surg. 2021 Oct;36(10):3540-3546. doi: 10.1111/jocs.15813. Epub 2021 Jul 12.
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J Thorac Cardiovasc Surg. 2021 Jul;162(1):107-115.e2. doi: 10.1016/j.jtcvs.2019.12.109. Epub 2020 Jan 23.
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Multimodal Imaging for the Assessment of a Cardiac Mass - A Case of Primary Cardiac Sarcoma.用于评估心脏肿物的多模态成像——原发性心脏肉瘤一例
J Radiol Case Rep. 2017 Nov 30;11(11):11-19. doi: 10.3941/jrcr.v11i11.3194. eCollection 2017 Nov.
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Lead extraction with high frequency laser sheaths: a single-centre experience.高频激光鞘管用于导线取出术:单中心经验
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