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高加索人群额部纤维性秃发的毛发镜检查:综述

Trichoscopy of Frontal Fibrosing Alopecia in Caucasians: A Review.

作者信息

Quadrelli Federico, Cedirian Stephano, Piraccini Bianca Maria

机构信息

Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S Orsola-Malpighi, Bologna, Italy.

Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.

出版信息

Skin Appendage Disord. 2024 Dec;10(6):439-442. doi: 10.1159/000539385. Epub 2024 Jun 18.

DOI:10.1159/000539385
PMID:39659647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11627533/
Abstract

BACKGROUND

Frontal fibrosing alopecia (FFA) is a scarring hair loss condition primarily affecting the frontotemporal hairline and often leading to partial or complete loss of eyebrows in a significant number of cases. It is characterized by slow progression and typically shows poor response to available treatments. Diagnosis relies on clinical, trichoscopic, and histopathological assessments, with specific criteria proposed by Vañó-Galván et al. in 2018 [J Am Acad Dermatol. 2018;78(1):e21-2].

SUMMARY

This literature review examines trichoscopic observations of FFA in Caucasians, focusing on both scalp and eyebrow manifestations. A comprehensive search of the PubMed database from 2010 to 2023 yielded 6 relevant articles. Trichoscopic findings varied across studies but highlighted common features such as empty follicles, perifollicular erythema, follicular hyperkeratosis, and the presence of "lonely hair" on the scalp. Additional research is warranted to thoroughly characterize demographic traits and FFA peculiarities within the Caucasian population, given the limited existing data in the literature.

KEY MESSAGES

Distinct trichoscopic features: trichoscopic examination of FFA among Caucasians reveals specific markers such as empty follicles, perifollicular erythema, and follicular hyperkeratosis, aiding in diagnosis and monitoring. Limited literature data: more investigation is needed to fully understand the demographic characteristics and FFA peculiarities among Caucasians, considering the scarcity of available data in existing literature.

摘要

背景

额部纤维性秃发(FFA)是一种瘢痕性脱发疾病,主要影响额颞部发际线,在许多病例中常导致眉毛部分或完全缺失。其特点是进展缓慢,对现有治疗通常反应不佳。诊断依赖于临床、毛发镜和组织病理学评估,2018年Vañó - Galván等人提出了具体标准[《美国皮肤病学会杂志》。2018年;78(1):e21 - 2]。

总结

本综述探讨了白种人中FFA的毛发镜观察结果,重点关注头皮和眉毛表现。对2010年至2023年的PubMed数据库进行全面检索,得到6篇相关文章。不同研究的毛发镜检查结果各异,但突出了一些共同特征,如毛囊空虚、毛囊周围红斑、毛囊角化过度以及头皮上出现“孤立毛发”。鉴于文献中现有数据有限,有必要进行更多研究以全面描述白种人群体中的人口统计学特征和FFA特点。

关键信息

独特的毛发镜特征:对白种人中FFA的毛发镜检查揭示了一些特定标志,如毛囊空虚、毛囊周围红斑和毛囊角化过度,有助于诊断和监测。文献数据有限:考虑到现有文献中可用数据的稀缺性,需要更多研究来充分了解白种人群体中的人口统计学特征和FFA特点。

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本文引用的文献

1
Occipital involvement in classic frontal fibrosing alopecia: Clinical and trichoscopic cross-sectional study in 17 patients.经典型额部纤维性脱发中的枕部受累:17例患者的临床和毛发镜横断面研究
J Am Acad Dermatol. 2023 Oct;89(4):815-817. doi: 10.1016/j.jaad.2023.05.064. Epub 2023 Jun 2.
2
Impact and Management of Loss of Eyebrows and Eyelashes.眉毛和睫毛缺失的影响与处理
Dermatol Ther (Heidelb). 2023 Jun;13(6):1243-1253. doi: 10.1007/s13555-023-00925-z. Epub 2023 May 15.
3
Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From a Multicenter Study of the International Dermoscopy Society.前额纤维性秃发诊断的临床与皮肤镜检查方法:国际皮肤镜协会多中心研究结果
Dermatol Pract Concept. 2022 Jan 1;12(1):e2022080. doi: 10.5826/dpc.1201a80. eCollection 2022 Feb.
4
Comparing the clinical differences in white and black women with frontal fibrosing alopecia.比较患有额部纤维性脱发的白种女性和黑种女性的临床差异。
Br J Dermatol. 2021 Nov;185(5):1074-1076. doi: 10.1111/bjd.20605. Epub 2021 Sep 7.
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Trichoscopy findings of frontal fibrosing alopecia on the eyebrows: A study of 151 cases.眉毛部位额部纤维性脱发的毛发镜检查结果:151 例研究。
J Am Acad Dermatol. 2021 Nov;85(5):1130-1134. doi: 10.1016/j.jaad.2019.12.023. Epub 2019 Dec 17.
6
Frontal fibrosing alopecia: a case series of 65 patients seen in a single Italian centre.额部纤维性脱发:意大利单一中心诊治的 65 例病例系列。
J Eur Acad Dermatol Venereol. 2019 Feb;33(2):433-438. doi: 10.1111/jdv.15372. Epub 2018 Dec 13.
7
The value of dermoscopy in diagnosing eyebrow loss in patients with alopecia areata and frontal fibrosing alopecia.皮肤镜检查在诊断斑秃和额部纤维性脱发患者眉毛缺失中的价值。
J Eur Acad Dermatol Venereol. 2019 Jan;33(1):213-219. doi: 10.1111/jdv.15279. Epub 2018 Oct 31.
8
Pseudoxanthoma elasticum-like papillary dermal elastolysis in frontal fibrosing alopecia.额部纤维性秃发中的弹性假黄瘤样乳头真皮弹性组织离解
J Dtsch Dermatol Ges. 2018 Sep;16(9):1136-1138. doi: 10.1111/ddg.13603. Epub 2018 Jul 30.
9
Distinct Trichoscopic Features of the Sideburns in Frontal Fibrosing Alopecia Compared to the Frontotemporal Scalp.与额颞部头皮相比,额部纤维性脱发患者鬓角独特的毛发镜特征。
Skin Appendage Disord. 2018 Jan;4(1):50-54. doi: 10.1159/000479116. Epub 2017 Aug 5.
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