Quadrelli Federico, Cedirian Stephano, Piraccini Bianca Maria
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S Orsola-Malpighi, Bologna, Italy.
Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
Skin Appendage Disord. 2024 Dec;10(6):439-442. doi: 10.1159/000539385. Epub 2024 Jun 18.
Frontal fibrosing alopecia (FFA) is a scarring hair loss condition primarily affecting the frontotemporal hairline and often leading to partial or complete loss of eyebrows in a significant number of cases. It is characterized by slow progression and typically shows poor response to available treatments. Diagnosis relies on clinical, trichoscopic, and histopathological assessments, with specific criteria proposed by Vañó-Galván et al. in 2018 [J Am Acad Dermatol. 2018;78(1):e21-2].
This literature review examines trichoscopic observations of FFA in Caucasians, focusing on both scalp and eyebrow manifestations. A comprehensive search of the PubMed database from 2010 to 2023 yielded 6 relevant articles. Trichoscopic findings varied across studies but highlighted common features such as empty follicles, perifollicular erythema, follicular hyperkeratosis, and the presence of "lonely hair" on the scalp. Additional research is warranted to thoroughly characterize demographic traits and FFA peculiarities within the Caucasian population, given the limited existing data in the literature.
Distinct trichoscopic features: trichoscopic examination of FFA among Caucasians reveals specific markers such as empty follicles, perifollicular erythema, and follicular hyperkeratosis, aiding in diagnosis and monitoring. Limited literature data: more investigation is needed to fully understand the demographic characteristics and FFA peculiarities among Caucasians, considering the scarcity of available data in existing literature.
额部纤维性秃发(FFA)是一种瘢痕性脱发疾病,主要影响额颞部发际线,在许多病例中常导致眉毛部分或完全缺失。其特点是进展缓慢,对现有治疗通常反应不佳。诊断依赖于临床、毛发镜和组织病理学评估,2018年Vañó - Galván等人提出了具体标准[《美国皮肤病学会杂志》。2018年;78(1):e21 - 2]。
本综述探讨了白种人中FFA的毛发镜观察结果,重点关注头皮和眉毛表现。对2010年至2023年的PubMed数据库进行全面检索,得到6篇相关文章。不同研究的毛发镜检查结果各异,但突出了一些共同特征,如毛囊空虚、毛囊周围红斑、毛囊角化过度以及头皮上出现“孤立毛发”。鉴于文献中现有数据有限,有必要进行更多研究以全面描述白种人群体中的人口统计学特征和FFA特点。
独特的毛发镜特征:对白种人中FFA的毛发镜检查揭示了一些特定标志,如毛囊空虚、毛囊周围红斑和毛囊角化过度,有助于诊断和监测。文献数据有限:考虑到现有文献中可用数据的稀缺性,需要更多研究来充分了解白种人群体中的人口统计学特征和FFA特点。