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2024年埃塞俄比亚亚的斯亚贝巴公立医院慢性阻塞性肺疾病患者肺动脉高压的患病率及其相关因素:一项基于机构的横断面研究

Prevalence of pulmonary hypertension and its associated factors among chronic obstructive pulmonary diseases patients at public hospitals of Addis Ababa, Ethiopia, 2024: a facility-based cross-sectional study.

作者信息

Kasse Tsehaynew, Elias Amanuel, Lonsako Arega Abebe, Agegnehu Yalemzer

机构信息

College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

出版信息

Front Public Health. 2024 Nov 26;12:1456235. doi: 10.3389/fpubh.2024.1456235. eCollection 2024.

Abstract

BACKGROUND

Pulmonary hypertension (PH) is a serious medical condition characterized by elevated pressure in the lung blood vessels, with chronic heart and lung diseases being the most common causes worldwide. However, there is a dearth of studies on the prevalence of pulmonary hypertension and its associated factors among chronic obstructive pulmonary disease (COPD) patients in Ethiopia and the study area.

OBJECTIVE

This study aimed to assess the prevalence of pulmonary hypertension and its associated factors among patients with chronic obstructive pulmonary disease at public hospitals in Addis Ababa, Ethiopia, 2024.

METHODS

A facility-based cross-sectional study involving 422 COPD patients charted in Addis Ababa town, Ethiopia from May - June 2024 was conducted. Respondents' records were chosen using simple random numbers. Structured, and pretested questionnaires, were used to collect data. The data were coded and entered into EpiData 3.1 before being exported to SPSS version 25 for analysis. Logistic regression was employed to identify factors influencing the prevalence of pulmonary hypertension. Statistical significance was set at  < 0.05 with a 95% confidence interval.

RESULTS

The study found the prevalence of pulmonary hypertension was 52% (95% CI: 49, 54.4%). Aged above 55 years [Adjusted Odds Ratio (AOR): 2.45 (1.55-3.9), Being male (AOR): 2.5 (1.5-4.1)]. Furthermore, having a history of alcohol [(AOR): 5.5 (2.4-13)], a history of smoking [(AOR): 4.6 (2.7-7.8), and congestive heart failure (AOR): 2.65 (1.5-4.6)], all increase the likelihood of pulmonary hypertension.

CONCLUSION

The study revealed a higher prevalence of pulmonary hypertension among COPD patients. Significant associations were found with being male, belonging to an older age group, and having a history of alcohol use, smoking, and congestive heart disease. Implementing screening programs, smoking cessation programs, educational initiatives, and counseling patients on lifestyle modifications were recommended.

摘要

背景

肺动脉高压(PH)是一种严重的病症,其特征是肺血管压力升高,慢性心肺疾病是全球最常见的病因。然而,在埃塞俄比亚及研究区域的慢性阻塞性肺疾病(COPD)患者中,关于肺动脉高压的患病率及其相关因素的研究匮乏。

目的

本研究旨在评估2024年埃塞俄比亚亚的斯亚贝巴公立医院慢性阻塞性肺疾病患者中肺动脉高压的患病率及其相关因素。

方法

进行了一项基于机构的横断面研究,纳入了2024年5月至6月在埃塞俄比亚亚的斯亚贝巴市登记的422例慢性阻塞性肺疾病患者。使用简单随机数选择受访者的记录。采用结构化且经过预测试的问卷收集数据。数据进行编码后录入EpiData 3.1,然后导出至SPSS 25版本进行分析。采用逻辑回归确定影响肺动脉高压患病率的因素。设定统计学显著性为<0.05,置信区间为95%。

结果

研究发现肺动脉高压的患病率为52%(95%CI:49,54.4%)。年龄在55岁以上[调整优势比(AOR):2.45(1.55 - 3.9)],男性(AOR):2.5(1.5 - 4.1)。此外,有饮酒史[(AOR):5.5(2.4 - 13)]、吸烟史[(AOR):4.6(2.7 - 7.8)]和充血性心力衰竭(AOR):2.65(1.5 - 4.6),均增加了患肺动脉高压的可能性。

结论

该研究揭示了慢性阻塞性肺疾病患者中肺动脉高压的患病率较高。发现与男性、年龄较大、有饮酒史、吸烟史和充血性心脏病存在显著关联。建议实施筛查项目、戒烟项目、教育举措,并就生活方式改变对患者进行咨询。

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