Wang Ru, Zhu Xiao-Yan, Wang Yi
Department of Pediatrics, Xinzhou District People's Hospital, Wuhan, Hubei, China.
Sanquan College of Xinxiang Medical University, Xinxiang, Henan, China.
Front Oncol. 2024 Nov 26;14:1439324. doi: 10.3389/fonc.2024.1439324. eCollection 2024.
Malignant melanoma (MM) is a highly malignant skin tumor. Although research on non-coding RNAs (ncRNAs) of MM has advanced swiftly in recent years, no specific bibliometric analyses have been conducted on this topic. The present study aims to summarize the knowledge graphs and frontier trends and to provide new perspectives and direction of collaboration for researchers.
Research data on melanoma and ncRNA published from January 1, 2006 to October 9, 2023 were retrieved and extracted from Web of Science. R Studio (Version 4.3.1), Scimago Graphica (Version 1.0.36), VOSviewer version (1.6.19), and Citespace (6.2.4R) were used to analyze the publications, countries, journals, institutions, authors, keywords, references, and other relevant data and to build collaboration network graphs and co-occurrence network graphs accordingly.
A total of 1,222 articles were retrieved, involving 4,894 authors, 385 journals, 43,220 references, 2413 keywords, and 1,651 institutions in 47 countries. The average annual growth rate in the number of articles was 25.02% from 2006 to 2023; among all the journals, Plos One had the highest number of publications and citations, which are 42 publications and 2,228 citations, respectively. Chinese researchers were the most prolific publishers in this field, having published a total of 657 articles, among which 42 were published by Shanghai Jiao Tong University, which was the most productive institution. In recent years, the most explored keywords included long non-coding RNAs, immunotherapy, and exosm. According to the timeline chart of reference co-citation, "functional role" has been the most explored hotspot since 2015, and human cancer is a newly emerged hotspot after 2021.
Through a bibliometric analysis, this study included all publications on ncRNAs and melanoma that were published in English from 2006 to 2023 in Web of Science to analyze the trends in the number of publications, international research focuses, and the direction of collaboration. The results of this study may provide information on knowledge graph, frontier trends and identify research topics in melanoma. More current research proved that ncRNA plays a crucial role in the biological behavior of melanoma including proliferation, invasion, metastasis, drug resistance, etc. With the development of research on ncRNA and melanoma, ncRNA may great potential in development of early diagnosis, targeted therapy and efficacy evaluation in the future. The results of this study also provide new perspectives and research partners for researchers in this field.
恶性黑色素瘤（MM）是一种高度恶性的皮肤肿瘤。尽管近年来关于MM的非编码RNA（ncRNAs）研究进展迅速，但尚未针对该主题进行具体的文献计量分析。本研究旨在总结知识图谱和前沿趋势，为研究人员提供新的合作视角和方向。
检索并从Web of Science中提取2006年1月1日至2023年10月9日发表的关于黑色素瘤和ncRNA的研究数据。使用R Studio（版本4.3.1）、Scimago Graphica（版本1.0.36）、VOSviewer版本（1.6.19）和Citespace（6.2.4R）分析出版物、国家、期刊、机构、作者、关键词、参考文献及其他相关数据，并据此构建合作网络图和共现网络图。
共检索到1222篇文章，涉及4894位作者、385种期刊、43220条参考文献、2413个关键词以及47个国家的1651个机构。2006年至2023年文章数量的年均增长率为25.02%；在所有期刊中，《公共科学图书馆·综合》的出版物数量和被引次数最高，分别为42篇和2228次。中国研究人员是该领域发表文章最多的群体，共发表657篇文章，其中上海交通大学发表42篇，是产出最多的机构。近年来，研究最多的关键词包括长链非编码RNA、免疫疗法和外泌体。根据参考文献共被引时间线图，“功能作用”自2015年以来一直是研究最多的热点，而人类癌症是2021年之后新出现的热点。
通过文献计量分析，本研究纳入了2006年至2023年在Web of Science上以英文发表的所有关于ncRNAs和黑色素瘤的出版物，以分析出版物数量趋势、国际研究重点和合作方向。本研究结果可为黑色素瘤的知识图谱、前沿趋势提供信息，并确定研究主题。更多当前研究证明，ncRNA在黑色素瘤的生物学行为包括增殖、侵袭、转移、耐药等方面发挥着关键作用。随着ncRNA与黑色素瘤研究的发展，ncRNA在未来早期诊断、靶向治疗和疗效评估的发展中可能具有巨大潜力。本研究结果也为该领域的研究人员提供了新的视角和研究伙伴。
