Chen Longhao, He Liuji, Liu Baijie, Zhou Yinghua, Lv Lijiang, Wang Zhiguang
The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
The Third Clinical Medical College, Zhejiang University of Chinese Medicine, Hangzhou, Zhejiang, China.
Front Oncol. 2024 Mar 12;14:1255061. doi: 10.3389/fonc.2024.1255061. eCollection 2024.
Osteosarcoma (OS) is the most common bone malignant tumor in children and adolescents. Recent research indicates that non-coding RNAs (ncRNAs) have been associated with OS occurrence and development, with significant progress made in this field. However, there is no intelligent structure prediction and literature visualization analysis in this research field. From the perspective of intelligent knowledge structure construction and bibliometrics, this study will comprehensively review the role of countries, institutions, journals, authors, literature citation relationships and subject keywords in the field of ncRNAs in OS. Based on this analysis, we will systematically analyze the characteristics of the knowledge structure of ncRNAs in OS disease research and identify the current research hotspots and trends.
The Web of Science Core Collection (WoSCC) database was searched for articles on ncRNAs in OS between 2001 and 2023. This bibliometric analysis was performed using VOSviewers, CiteSpace, and Pajek.
This study involved 15,631 authors from 2,631 institutions across 57 countries/regions, with a total of 3,642 papers published in 553 academic journals. China has the highest number of published papers in this research field. The main research institutions include (n = 129, 3.54%), (n = 128, 3.51%), (n = 110, 3.02%), and (n = 109, 2.99%). (n =139, 3.82%), (120, 3.31%), and (n = 95, 2.61%) are the most popular journals in this field, with being the most co-cited journal (Co-Citation = 4,268). , and published the most papers, with being the most co-cited author. and are the main focuses of ncRNAs in OS studies. Key themes include and . Since 2020, hotspots and trends in ncRNA research in OS include and
This study represents the first comprehensive bibliometric analysis of the knowledge structure and development of ncRNAs in OS. These findings highlight current research hotspots and frontier directions, offering valuable insights for future studies on the role of ncRNAs in OS.
骨肉瘤（OS）是儿童和青少年中最常见的骨恶性肿瘤。最近的研究表明，非编码RNA（ncRNAs）与骨肉瘤的发生和发展有关，该领域已取得显著进展。然而，该研究领域尚无智能结构预测和文献可视化分析。从智能知识结构构建和文献计量学的角度来看，本研究将全面回顾国家、机构、期刊、作者、文献引用关系和主题关键词在骨肉瘤领域非编码RNA研究中的作用。基于此分析，我们将系统分析骨肉瘤疾病研究中非编码RNA知识结构的特征，并确定当前的研究热点和趋势。
在科学网核心合集（WoSCC）数据库中检索2001年至2023年间关于骨肉瘤中非编码RNA的文章。使用VOSviewer、CiteSpace和Pajek进行文献计量分析。
本研究涉及来自57个国家/地区2631个机构的15631名作者，共在553种学术期刊上发表了3642篇论文。中国在该研究领域发表的论文数量最多。主要研究机构包括（n = 129，3.54%）、（n = 128，3.51%）、（n = 110，3.02%）和（n = 109，2.99%）。（n =139，3.82%）、（120，3.31%）和（n = 95，2.61%）是该领域最受欢迎的期刊，其中被引频次最高（共被引次数 = 共被引次数 = 4268）。发表的论文最多，是被引频次最高的作者。和是骨肉瘤研究中非编码RNA的主要重点。关键主题包括和。自2020年以来，骨肉瘤中非编码RNA研究的热点和趋势包括和
本研究是对骨肉瘤中非编码RNA知识结构和发展的首次全面文献计量分析。这些发现突出了当前的研究热点和前沿方向，为未来关于非编码RNA在骨肉瘤中作用的研究提供了有价值的见解。
