危重症产科患者研究中的结果报告：一项系统综述。
Outcome reporting in studies on critically ill obstetric patients: A systematic review.
作者信息
Viau-Lapointe Julien, Kfouri Julia, Thompson Mary, Ashraf Rizwana, D'Souza Rohan, Lapinsky Stephen
机构信息
Department of Medicine, Hôpital Maisonneuve-Rosemont, Université de Montréal, Montreal, Canada.
Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Ontario, Canada.
出版信息
Obstet Med. 2024 Dec 8:1753495X241302848. doi: 10.1177/1753495X241302848.
INTRODUCTION
This systematic review is the first step in the process of standardizing outcome reporting through the development of a core outcome set for research on critically ill obstetric patients (COSCO).
METHODS
A five-database search was performed to identify randomized and non-randomized studies published before November 2017, on patients admitted to intensive care or high-dependency units during or immediately after pregnancy. Reported outcomes were categorized into domains and definitions were documented.
RESULTS
Of the 12,581 citations reviewed, 136 studies were included. The most reported outcome domains were maternal all-cause mortality ( = 128, 94.5%), resource use ( = 116, 85.6%), and clinical/physiological outcomes ( = 111, 82.8%). Outcomes related to functioning/life impact and adverse effects of treatment were only reported in four (2.9%) studies. There was inconsistency in outcome definitions.
CONCLUSIONS
This review identified considerable variation in outcome reporting and definitions and generated an outcome list to consider in COSCO development.
引言
本系统评价是通过制定危重症产科患者研究的核心结局集（COSCO）来规范结局报告过程的第一步。
方法
进行了五数据库检索，以识别2017年11月之前发表的关于妊娠期间或产后立即入住重症监护病房或高依赖病房患者的随机和非随机研究。将报告的结局分类到各个领域，并记录定义。
结果
在检索的12581条文献中，纳入了136项研究。报告最多的结局领域是孕产妇全因死亡率（n = 128，94.5%）、资源利用（n = 116，85.6%）和临床/生理结局（n = 111，82.8%）。与功能/生活影响及治疗不良反应相关的结局仅在四项（2.9%）研究中被报告。结局定义存在不一致性。
结论
本评价发现结局报告和定义存在相当大的差异，并生成了一份在COSCO制定过程中需考虑的结局清单。
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