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肺减容:手术及支气管内瓣膜

Lung volume reduction: surgery endobronchial valves.

作者信息

Ceulemans Laurens J, Esendagli Dorina, Cardillo Giuseppe, Migliore Marcello

机构信息

Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.

Department of Chronic Diseases and Metabolism Laboratory of Pneumology and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.

出版信息

Breathe (Sheff). 2024 Dec 10;20(3):240107. doi: 10.1183/20734735.0107-2024. eCollection 2024 Oct.

Abstract

Volume reduction is a disease-modifying treatment that aims to reshape the diseased lung towards a more normal total lung capacity by removing severely damaged and overinflated lung parenchyma. It is an effective therapeutic strategy in well-selected patients, resulting in improvements in exercise tolerance, lung function, quality of life and survival. The most widespread strategies for volume reduction are either video-assisted thoracoscopic surgery or bronchoscopic lung volume reduction. It is crucial to decide which approach would be more suitable for specific patients, as this is related to the outcome of the procedure. Factors like emphysema distribution on computed tomography, the presence or absence of collateral ventilation, the patient's pulmonary function tests, a history of other comorbidities and previous interventions might all influence the choice of procedure. It is crucial that this decision is taken by a multidisciplinary expert team to have the best outcome and fewer complications.

摘要

肺减容术是一种改变疾病进程的治疗方法,旨在通过切除严重受损和过度膨胀的肺实质,使患病的肺重塑为更接近正常的肺总量。对于精心挑选的患者,这是一种有效的治疗策略,可改善运动耐量、肺功能、生活质量并延长生存期。最常用的肺减容策略是电视辅助胸腔镜手术或支气管镜肺减容术。决定哪种方法更适合特定患者至关重要,因为这与手术结果相关。诸如计算机断层扫描上肺气肿的分布、有无侧支通气、患者的肺功能测试、其他合并症病史和既往干预措施等因素,都可能影响手术方式的选择。至关重要的是,这一决策应由多学科专家团队做出,以实现最佳结果并减少并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85a/11629166/d1250a3e0483/EDU-0107-2024.01.jpg

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