Thimmappa Latha, Hebbar Saraswathi, Bhat Shyamasunder N
College of Nursing, All India Institute of Medical Sciences, Kalyani, West Bengal, India.
Manipal School of Nursing, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Infez Med. 2024 Dec 1;32(4):489-498. doi: 10.53854/liim-3204-7. eCollection 2024.
This study aims to bridge the informational gap regarding the clinical and epidemiological aspects of spondylodiscitis in India, addressing the dearth of substantial evidence in this domain. This study was conducted in a tertiary care hospital over three years, involving 145 adult patients diagnosed with spondylodiscitis. Among them, 28 (19.3%) had Brucellar spondylodiscitis with a younger mean age of 40.1 years, 76 (52.4%) had tubercular spondylodiscitis with a higher mean age of 50.7 years, and 27 (18.6%) had pyogenic spondylodiscitis. Common symptoms included pain while walking (82.1% Brucellar, 93.4% TB, 77.8% pyogenic), fever (39.3% Brucellar, 38.2% TB, 33.3% pyogenic), and limb weakness (25% Brucellar, 46.1% TB, 66.7% pyogenic). CRP (mg/L) levels were elevated in Brucellar (mean 58.75) and pyogenic (mean 60.4) spondylodiscitis patients, with debridement and decompression performed in 50% Brucellar, 55.3% tubercular, and 70.4% pyogenic patients. The study reveals the clinical and epidemiological aspects of spondylodiscitis in South India, contributing to the enrichment of existing knowledge in diagnosis and management.
本研究旨在填补印度脊椎椎间盘炎临床和流行病学方面的信息空白，解决该领域缺乏充分证据的问题。本研究在一家三级护理医院进行，为期三年，涉及145名被诊断为脊椎椎间盘炎的成年患者。其中，28例（19.3%）患有布鲁氏菌性脊椎椎间盘炎，平均年龄较轻，为40.1岁；76例（52.4%）患有结核性脊椎椎间盘炎，平均年龄较高，为50.7岁；27例（18.6%）患有化脓性脊椎椎间盘炎。常见症状包括行走时疼痛（布鲁氏菌性82.1%、结核性93.4%、化脓性77.8%）、发热（布鲁氏菌性39.3%、结核性38.2%、化脓性33.3%）和肢体无力（布鲁氏菌性25%、结核性46.1%、化脓性66.7%）。布鲁氏菌性（平均58.75）和化脓性（平均60.4）脊椎椎间盘炎患者的C反应蛋白（mg/L）水平升高，50%的布鲁氏菌性患者、55.3%的结核性患者和70.4%的化脓性患者进行了清创和减压手术。该研究揭示了印度南部脊椎椎间盘炎的临床和流行病学方面，有助于丰富诊断和治疗方面的现有知识。
