Stankovic Goran, Cangemi Stefano, DeVos Amanda, Burzotta Francesco, Iaizzo Paul A
Department of Cardiology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Interventional Cardiology Unit, S. Antonio Abate Hospital, Erice, Sicily, Italy.
Catheter Cardiovasc Interv. 2025 Jan;105(1):135-143. doi: 10.1002/ccd.31326. Epub 2024 Dec 11.
In some cases it is critical to clinically perform coronary bifurcation stenting to minimize the potential risk for restenosis and/or stent thrombosis. The European Bifurcation Club (EBC) has provided guidelines for optimally performing such procedures. Yet, sometimes such procedures do not go as planned, and in some cases bailout procedures are required. Here we utilized Visible Heart® (VH) methodologies and multimodal visualizations to better understand each step for optimally performed T and small protrusion (TAP) procedures, as well as those in which complications occurred. These studies were performed within reanimated swine hearts in which endoscopes, fluoroscopy, and optical coherence tomography (OCT) could readily be used. Additionally, because these procedures were performed in reanimated hearts, one could intentionally cause complications, so to perform bailout procedures. Finally, following these procedures each specimen was micro CT scanned, and high resolution computational models (~40 microns) were reconstructed of the final outcomes.
在某些情况下，临床上进行冠状动脉分叉处支架置入术对于将再狭窄和/或支架血栓形成的潜在风险降至最低至关重要。欧洲分叉俱乐部（EBC）已提供了优化此类手术操作的指南。然而，有时此类手术并不按计划进行，在某些情况下需要补救手术。在此，我们利用可视心脏（Visible Heart®，VH）方法和多模态可视化技术，以更好地理解优化执行T型和小突出部（TAP）手术以及出现并发症的手术的每一步骤。这些研究是在复苏的猪心脏中进行的，在内镜、荧光透视和光学相干断层扫描（OCT）可方便使用的情况下。此外，由于这些手术是在复苏的心脏中进行的，因此可以故意引发并发症，以便进行补救手术。最后，在这些手术后，对每个标本进行微型计算机断层扫描，并重建了最终结果的高分辨率计算模型（约40微米）。
