Almusallam Abdullah Fadhel, Atmeh Mosab Tareq, Obeidat Mohammed Bader, El-Isa Hasan Zuhair, Smadi Ahmed, Atmeh Mousa Tarek
Kuwait Ministry of Health, Kuwait.
Jordan University of Science and Technology, Jordan.
Int J Surg Case Rep. 2025 Jan;126:110712. doi: 10.1016/j.ijscr.2024.110712. Epub 2024 Dec 1.
Isolated neurofibromas of the nasal tip are uncommon, particularly in pediatric patients. Neurofibromas are benign tumors that arise from the peripheral nerve sheath and are usually associated with neurofibromatosis type 1 (NF1). Isolated cases present unique challenges due to their location and the importance of cosmetic outcomes. This case highlights the presentation, diagnostic process, and management of a rare nasal tip neurofibroma in an 11-year-old girl.
An 11-year-old female presented with a gradually enlarging mass on the nasal tip over several months, causing cosmetic concern without pain, bleeding, or obstruction. Clinical examination revealed a firm, non-tender lesion, about 1 cm in diameter, with normal skin. Imaging confirmed a well-defined mass localized to the nasal tip. Surgical excision was performed, and histopathology confirmed a diagnosis of neurofibroma. Follow-up showed no recurrence, and the patient was satisfied with the cosmetic result.
Neurofibromas, though benign, can cause aesthetic concerns, particularly in prominent areas like the nasal tip. Isolated neurofibromas in children without NF1 are rare. Surgical excision is the treatment of choice, with emphasis on complete removal to prevent recurrence. This case demonstrates successful excision with clear margins, preserving nasal structure and appearance. Long-term monitoring is essential for recurrence prevention.
Isolated neurofibroma of the nasal tip is a rare condition in children. Surgical excision remains the treatment of choice, with careful planning required to preserve both cosmetic and functional outcomes. Regular follow-up is crucial to monitor for recurrence, especially in the absence of neurofibromatosis.
鼻尖孤立性神经纤维瘤并不常见，在儿科患者中尤为如此。神经纤维瘤是起源于周围神经鞘的良性肿瘤，通常与1型神经纤维瘤病（NF1）相关。孤立病例因其位置和美容效果的重要性而带来独特挑战。本病例突出了一名11岁女孩罕见的鼻尖神经纤维瘤的表现、诊断过程及治疗。
一名11岁女性，数月来鼻尖肿物逐渐增大，引起美容方面的担忧，但无疼痛、出血或阻塞症状。临床检查发现一个质地坚硬、无压痛的病变，直径约1厘米，皮肤正常。影像学检查证实肿物界限清晰，位于鼻尖。进行了手术切除，组织病理学确诊为神经纤维瘤。随访显示无复发，患者对美容效果满意。
神经纤维瘤虽为良性，但可引起美容问题，尤其是在鼻尖等突出部位。无NF1的儿童孤立性神经纤维瘤罕见。手术切除是首选治疗方法，重点是完整切除以防止复发。本病例展示了切除边缘清晰，成功切除肿物，同时保留了鼻结构和外观。长期监测对于预防复发至关重要。
鼻尖孤立性神经纤维瘤在儿童中是一种罕见疾病。手术切除仍是首选治疗方法，需要精心规划以保留美容和功能效果。定期随访对于监测复发至关重要，尤其是在无神经纤维瘤病的情况下。
