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前庭康复对持续性姿势-感知性头晕的效果与对慢性单侧前庭功能减退的效果一样吗?

Is Vestibular Rehabilitation as Effective for Persistent Postural-Perceptual Dizziness as for Chronic Unilateral Vestibular Hypofunction?

作者信息

Yamato Akiyuki, Yagi Chihiro, Kimura Akira, Kai Ryota, Kitazawa Meiko, Yamagishi Tatsuya, Ohshima Shinsuke, Izumi Shuji, Imai Takao, Inohara Hidenori, Horii Arata

机构信息

Department of Otolaryngology, Suita Municipal Hospital, Osaka.

Department of Otolaryngology, Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata.

出版信息

Otol Neurotol. 2025 Feb 1;46(2):170-175. doi: 10.1097/MAO.0000000000004397. Epub 2024 Dec 11.

DOI:10.1097/MAO.0000000000004397
PMID:39663796
Abstract

OBJECTIVE

To compare the feasibility and outcomes of vestibular rehabilitation (VR) for persistent postural-perceptual dizziness (PPPD) with those for chronic unilateral vestibular hypofunction (UVH).

STUDY DESIGN

Prospective study.

SETTING

Tertiary referral center.

PATIENTS

Nineteen consecutive patients with chronic UVH lasting for >3 months and 15 with PPPD.

INTERVENTIONS

The VR program consisted of gaze stabilization exercises, static or dynamic balance exercises and gait training, and habituation exercises that exposed patients to a provocative stimulus. Patients were asked to perform VR for at least 20 min a day.

MAIN OUTCOME MEASURES

Status of VR (i.e., continuation/discontinuation) and outcomes were assessed 1 month after the introduction of VR using the Dizziness Handicap Inventory for handicaps in daily life due to dizziness, the Niigata PPPD Questionnaire (NPQ) for symptom exacerbations of PPPD, and the Hospital Anxiety and Depression Scale for anxiety and depression.

RESULTS

No patients in the chronic UVH group discontinued VR, whereas six patients in the PPPD group discontinued VR owing to symptom exacerbations, showing a significant difference. VR did not decrease any symptom scale, except for the NPQ-motion subscore, in patients with PPPD who continued VR, whereas it decreased all clinical symptom scales, except for the NPQ-motion subscore, in patients with chronic UVH.

CONCLUSIONS

Patients with PPPD had a higher rate of VR discontinuation than those with chronic UVH, and VR was less effective in patients with PPPD who even continued treatment than in those with chronic UVH. Therefore, VR on PPPD should be optimized.

摘要

目的

比较持续性姿势-感知性头晕(PPPD)与慢性单侧前庭功能减退(UVH)进行前庭康复(VR)的可行性和效果。

研究设计

前瞻性研究。

研究地点

三级转诊中心。

患者

19例连续的慢性UVH患者,病程超过3个月,以及15例PPPD患者。

干预措施

VR方案包括注视稳定练习、静态或动态平衡练习和步态训练,以及使患者暴露于诱发刺激的习服练习。要求患者每天至少进行20分钟的VR。

主要观察指标

在引入VR 1个月后,使用头晕残障量表评估因头晕导致的日常生活残障情况,使用新潟PPPD问卷(NPQ)评估PPPD症状加重情况,使用医院焦虑抑郁量表评估焦虑和抑郁情况,以此评估VR状态(即继续/停止)和效果。

结果

慢性UVH组无患者停止VR,而PPPD组有6例患者因症状加重停止VR,差异有统计学意义。在继续进行VR的PPPD患者中,除NPQ运动子评分外,VR未降低任何症状量表评分;而在慢性UVH患者中,除NPQ运动子评分外,VR降低了所有临床症状量表评分。

结论

PPPD患者VR停止率高于慢性UVH患者,且即使继续治疗,VR对PPPD患者的效果也不如慢性UVH患者。因此,应优化针对PPPD的VR治疗。

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