Olugbade Idowu D, Petty Anna C, Imahiyerobo-Ip Joyce
The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Vibrant Dermatology, Dedham, Massachusetts, USA.
J Cosmet Dermatol. 2025 Feb;24(2):e16711. doi: 10.1111/jocd.16711. Epub 2024 Dec 12.
The 650-ms, 1064-nm Nd:YAG laser device may provide superior efficacy and tolerability for the treatment of acne vulgaris over conventional treatments.
To evaluate the efficacy and tolerability of a 650-ms laser for the treatment of mild to severe facial acne vulgaris.
PATIENTS/METHODS: Records of 225 subjects with mild to severe facial acne vulgaris and treated with a 650-ms laser were reviewed.
Subjects required a median of 3 treatments to achieve clearance. Clearance was achieved in 108/225 (48%) subjects. Adverse effects were limited to acne flare-ups and dryness. Treatment with isotretinoin was not required in 180/209 (80%) of subjects. A variety of topical and oral medications and non-laser procedures may be used in conjunction with the 650-ms laser without adverse effects. At the 6-month follow-up visit, the median Investigator Global Scale (IGA) score was 1.0 (almost clear). For most IGA-rated parameters differences between white patients and patients with skin of color were not statistically significant.
The 650-ms, 1064-nm Nd:YAG laser provides a safe and efficacious treatment of mild to severe acne in patients with white skin and skin of color.
650毫秒、1064纳米的钕:钇铝石榴石激光设备在治疗寻常痤疮方面可能比传统治疗方法具有更高的疗效和耐受性。
评估650毫秒激光治疗轻至重度面部寻常痤疮的疗效和耐受性。
患者/方法:回顾了225例轻至重度面部寻常痤疮且接受650毫秒激光治疗的患者记录。
患者平均需要3次治疗才能达到清除效果。108/225(48%)的患者实现了清除。不良反应仅限于痤疮爆发和皮肤干燥。209例患者中有180例(80%)无需使用异维A酸治疗。650毫秒激光可与多种局部和口服药物以及非激光治疗联合使用,且无不良反应。在6个月的随访中,研究者整体评估(IGA)评分中位数为1.0(几乎清除)。对于大多数IGA评分参数,白种患者和有色人种患者之间的差异无统计学意义。
650毫秒、1064纳米的钕:钇铝石榴石激光为白种人和有色人种患者的轻至重度痤疮提供了一种安全有效的治疗方法。