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一名异时性胰腺腺癌患者栓塞胃十二指肠动脉部位周围强烈的成纤维细胞活化蛋白抑制剂定位:正电子成像中的一个潜在陷阱。

Intense fibroblast activation protein inhibitor localization around the site of embolized gastroduodenal artery in a patient with metachronous pancreatic adenocarcinoma: A potential pitfall in positron imaging.

作者信息

Abdlkadir Ahmed Saad, Alalawi Hasan, Al-Ibraheem Akram

机构信息

Department of Nuclear Medicine and PET/CT, King Hussein Cancer Center (KHCC), Amman, Jordan.

School of Medicine, The University of Jordan, Amman, Jordan.

出版信息

Acta Radiol Open. 2024 Dec 9;13(12):20584601241307350. doi: 10.1177/20584601241307350. eCollection 2024 Dec.

Abstract

Gallium-Fibroblast activation protein inhibitor (Ga-FAPI) positron emission tomography/computed tomography (PET/CT) is increasingly used for evaluating various epithelial neoplasms. Despite addressing some pitfalls, many remain unacknowledged. This report details a 77-year-old man with suspected pancreatic malignancy who underwent a Ga-FAPI PET/CT scan post-gastroduodenal coil embolization for upper gastrointestinal bleeding. The scan revealed intense Ga-FAPI uptake in the pancreatic body and tail malignancy and around the embolized gastroduodenal artery, indicating a healing process. This highlights the importance of understanding FAPI expression in recent surgical sites for accurate radiologic interpretation.

摘要

镓-成纤维细胞活化蛋白抑制剂(Ga-FAPI)正电子发射断层扫描/计算机断层扫描(PET/CT)越来越多地用于评估各种上皮性肿瘤。尽管解决了一些问题,但许多问题仍未得到认识。本报告详细介绍了一名77岁疑似胰腺恶性肿瘤的男性患者,他因上消化道出血接受胃十二指肠线圈栓塞术后进行了Ga-FAPI PET/CT扫描。扫描显示胰腺体尾部恶性肿瘤及栓塞的胃十二指肠动脉周围有强烈的Ga-FAPI摄取,提示愈合过程。这突出了了解近期手术部位FAPI表达对于准确放射学解读的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/289d/11629421/d2a535e8d9eb/10.1177_20584601241307350-fig1.jpg

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