Kim Joseph L, Kim Yohan, Saenz Andres
Neurology, UT Health San Antonio, San Antonio, USA.
Cureus. 2024 Dec 10;16(12):e75475. doi: 10.7759/cureus.75475. eCollection 2024 Dec.
Autoimmune encephalitis is a disorder characterized by an autoantibody-mediated process that leads to brain inflammation. It is associated with neurological symptoms including cognitive issues, psychiatric problems, seizures, and autonomic dysfunctions. Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (anti-LGI1 LE) is a rare type of autoimmune LE with a unique presentation, comprising neuropsychiatric disturbances, sleep disorders, and faciobrachial dystonic seizures (FBDS). While the involvement of the larynx is seen in various other autoimmune and neurological diseases, it is not a known issue with anti-LGI1 LE. The purpose of this case report is to highlight an atypical symptom - acute bilateral vocal cord failure - that unexpectedly occurred in a patient with anti-LGI1 LE.
自身免疫性脑炎是一种以自身抗体介导的过程为特征的疾病，该过程会导致脑部炎症。它与包括认知问题、精神问题、癫痫发作和自主神经功能障碍在内的神经症状有关。抗富含亮氨酸胶质瘤失活1边缘性脑炎（抗LGI1 LE）是一种罕见的自身免疫性边缘性脑炎，具有独特的表现，包括神经精神障碍、睡眠障碍和面臂肌张力障碍性癫痫发作（FBDS）。虽然喉部受累在其他各种自身免疫性和神经系统疾病中都有发现，但在抗LGI1 LE中并不是一个已知问题。本病例报告的目的是突出一种非典型症状——急性双侧声带麻痹——该症状意外出现在一名抗LGI1 LE患者身上。
