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扁桃体癌海绵窦转移致动眼神经麻痹1例

A Case of Oculomotor Nerve Paralysis Caused by Cavernous Sinus Metastasis of Tonsil Cancer.

作者信息

Kim Younghac, Chung Man Ki, Hong Sang Duk

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Republic of Korea.

出版信息

J Rhinol. 2022 Mar;29(1):52-55. doi: 10.18787/jr.2021.00381. Epub 2022 Feb 11.

DOI:10.18787/jr.2021.00381
PMID:39664466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11524388/
Abstract

Oropharyngeal squamous cell carcinoma (OSCC) with metastasis to the cavernous sinus (CS) is uncommon, and only a few cases have been described in the literature. The highest age-adjusted incidence rate for OSCC including the tonsil in males occurs in South Asians, and more cases should be reported to establish earlier identification and treatment. We report a case of OSCC in a 59-year-old male who underwent prompt endoscopic biopsy and early palliative radiation therapy to allow complete recovery of cranial nerve palsies to improve his quality of life, despite having a poor prognosis. Furthermore, this report emphasizes his dramatic resolution of symptoms after radiation therapy, highlighting the importance of rapid recognition and proper management.

摘要

伴有海绵窦转移的口咽鳞状细胞癌(OSCC)并不常见,文献中仅描述了少数病例。包括扁桃体在内的OSCC在男性中的年龄调整发病率最高的是南亚人,应报告更多病例以建立早期识别和治疗方法。我们报告了一例59岁男性的OSCC病例,尽管预后不良,但该患者接受了及时的内镜活检和早期姑息性放射治疗,以使颅神经麻痹完全恢复,从而改善其生活质量。此外,本报告强调了他放疗后症状的显著缓解,突出了快速识别和妥善管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/a88495bda339/jr-2021-00381f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/3329669db5bf/jr-2021-00381f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/4856f9b6e6b1/jr-2021-00381f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/55e683a14a30/jr-2021-00381f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/c3e754405c48/jr-2021-00381f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/a88495bda339/jr-2021-00381f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/3329669db5bf/jr-2021-00381f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/4856f9b6e6b1/jr-2021-00381f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/55e683a14a30/jr-2021-00381f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/c3e754405c48/jr-2021-00381f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0285/11524388/a88495bda339/jr-2021-00381f5.jpg

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本文引用的文献

1
Cavernous sinus involvement in human papillomavirus associated oropharyngeal squamous cell carcinoma: case report of an atypical site of distant metastasis.人乳头瘤病毒相关性口咽鳞状细胞癌累及海绵窦:远处转移非典型部位的病例报告。
J Otolaryngol Head Neck Surg. 2018 May 9;47(1):32. doi: 10.1186/s40463-018-0280-0.
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Percutaneous Biopsy of Lesions in the Cavernous Sinus: A Systematic Review.海绵窦病变的经皮活检:一项系统评价
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Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy.p16 阳性 HPV 相关口咽鳞癌根治性放疗后非典型临床行为
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Abducent nerve paralysis: first clinical sign of clivus metastasis from tonsillar carcinoma.展神经麻痹:扁桃体癌斜坡转移的首个临床体征。
Acta Otolaryngol. 2008 Jun;128(6):713-6. doi: 10.1080/00016480701687283.
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Cavernous sinus metastasis from oropharyngeal squamous cell carcinoma.口咽鳞状细胞癌的海绵窦转移
Med Oral Patol Oral Cir Bucal. 2007 Mar 1;12(2):E166-70.
10
Malignant neoplasms of the sphenoid sinus.
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