Yoon Chan Ho, Yun Young Bin, Kim Sangjun, Bae Woo Yong
Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Republic of Korea.
J Rhinol. 2023 Mar;30(1):53-56. doi: 10.18787/jr.2023.00011. Epub 2023 Mar 30.
Guillain-Barré syndrome (GBS) is an autoimmune disease that is generally preceded by an infection. Its typical symptoms are progressive symmetric paresis and an absence of deep tendon reflexes. GBS could be a life-threatening condition due to the paralysis of respiratory muscles, and admission to the intensive care unit should be considered for close monitoring. Intravenous immunoglobulin can improve the course of the disease. Postoperative GBS is most likely to occur after gastrointestinal, cardiac, thoracic, neurological, or orthopedic surgery, as well as surgery in the female reproductive tract. The duration of surgery, age, infectious diseases, preexisting autoimmune diseases, and malignant diseases are associated with postoperative GBS. Patients with these factors have a higher risk of postoperative GBS and therefore require precautions to be taken after surgery. We report a case of 53-year-old woman who had experienced GBS after Nasal surgery preceded by gastrointestinal infection and treated by intravenous immunoglobulin.
格林-巴利综合征(GBS)是一种通常在感染后出现的自身免疫性疾病。其典型症状为进行性对称性肌无力和腱反射消失。由于呼吸肌麻痹,GBS可能危及生命,应考虑收入重症监护病房进行密切监测。静脉注射免疫球蛋白可改善病程。术后GBS最有可能发生在胃肠道、心脏、胸部、神经或骨科手术以及女性生殖道手术后。手术时间、年龄、传染病、既往自身免疫性疾病和恶性疾病与术后GBS有关。有这些因素的患者术后发生GBS的风险较高,因此术后需要采取预防措施。我们报告一例53岁女性,在鼻部手术前发生胃肠道感染,术后出现GBS,并接受了静脉注射免疫球蛋白治疗。