Khan Amjad, Ahmad Syeda Qumreen, Akhtar Tayyab Saeed, Bushra Hamama Tul, Imran Muhammad, Khan Javeria Zahid, Shah Sanjida, Haddayat Nadia, Mushtaq Saima, Dong Yalin, Feng Weiyi, Fang Yu
Department of Pharmacy The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Health Science center Xi'an Jiaotong University Xi'an China.
JGH Open. 2024 Dec 10;8(12):e70045. doi: 10.1002/jgh3.70045. eCollection 2024 Dec.
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly used to diagnose and treat bile duct and pancreatic disorders. Successful cannulation of the papilla is crucial for the effectiveness of ERCP; however, sometimes, it can be challenging to achieve. This study explores the relationship between net difficult ERCP cannulation with bile visibility, papilla orifice visibility, and papilla position and compares it with successful cannulation.
These data were collected from the ERCP database at the Center for Liver Disease, Holy Family Hospital, Rawalpindi, between November 2019 and November 2022. IBM SPSS version 26.0 software was used for statistical analysis.
The study included 329 patients, with 186 (56.6%) female and 143 (43.5%) male participants. Most patients were in the 39-48 age group (28.3%), with a mean age of 51 ± 1. Bile visibility was noted in 268 (81.5%) cases, papilla orifice visibility in 296 (90%) participants, atypical papilla in 20 (6.1%), and typical papilla in 309 (93.9%) participants. Bile visibility ( = 0.004) and papilla orifice visibility ( = 0.006) were significantly associated with successful cannulation, while papilla position ( = 0.116) was not. Significant associations were also found between difficult cannulation and bile visibility ( = 0.000), papilla orifice visibility ( = 0.000), and papilla position ( = 0.000).
Understanding this relationship can improve success rates and reduce complications associated with difficult cannulation during ERCP procedures. Further research is needed to establish clear correlations and guidelines for endoscopists to plan appropriate strategies for challenging cases.
内镜逆行胰胆管造影术(ERCP)常用于诊断和治疗胆管及胰腺疾病。成功插管至乳头对于ERCP的有效性至关重要;然而,有时实现这一点可能具有挑战性。本研究探讨了ERCP插管困难与胆汁显影、乳头开口显影及乳头位置之间的关系,并将其与成功插管进行比较。
这些数据收集自2019年11月至2022年11月期间拉瓦尔品第圣家医院肝病中心的ERCP数据库。使用IBM SPSS 26.0版软件进行统计分析。
该研究纳入329例患者,其中女性186例(56.6%),男性143例(43.5%)。大多数患者年龄在39 - 48岁组(28.3%),平均年龄为51±1岁。268例(81.5%)病例可见胆汁,296例(90%)参与者可见乳头开口,20例(6.1%)为非典型乳头,309例(93.9%)参与者为典型乳头。胆汁显影(=0.004)和乳头开口显影(=0.006)与成功插管显著相关,而乳头位置(=0.116)则不然。在插管困难与胆汁显影(=0.000)、乳头开口显影(=0.000)及乳头位置(=0.000)之间也发现了显著关联。
了解这种关系可以提高成功率,并减少ERCP操作过程中与插管困难相关的并发症。需要进一步研究以建立明确的相关性和指南,供内镜医师为具有挑战性的病例制定合适的策略。