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重要人类病原体血清型M1的SF370菌株的新型组装体。

Novel assembly of the SF370 strain of the important human pathogen serotype M1.

作者信息

Wulff Thomas Fabian, Ahmed-Begrich Rina, Hahnke Karin, Jahn Michael, Charpentier Emmanuelle

机构信息

Max Planck Unit for the Science of Pathogens, Berlin, Germany.

Institute for Biology, Humboldt University Berlin, Berlin, Germany.

出版信息

Microbiol Resour Announc. 2025 Jan 16;14(1):e0119724. doi: 10.1128/mra.01197-24. Epub 2024 Dec 12.

Abstract

The important human pathogen causes a wide range of diseases. Strain SF370 was the first fully sequenced strain of , providing essential insights into the molecular mechanisms of disease. We present an improved genome assembly of strain SF370 from ATCC, which corrects long-standing errors in its genome.

摘要

这种重要的人类病原体可引发多种疾病。菌株SF370是首个完成全基因组测序的该病原体菌株,为深入了解疾病的分子机制提供了重要线索。我们展示了来自美国典型培养物保藏中心(ATCC)的菌株SF370的改进基因组组装结果,该结果纠正了其基因组中长期存在的错误。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66b1/11737162/795a25d293a4/mra.01197-24.f001.jpg

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